Results 71 to 80 of about 3,615,865 (367)

HIV Infection Is Associated With Diffusing Capacity Impairment in Women

Journal of Acquired Immune Deficiency Syndromes, 2013
:Respiratory dysfunction is common with HIV infection, but few studies have directly assessed whether HIV remains an independent risk factor for pulmonary function abnormalities in the antiretroviral therapy era. Additionally, few studies have focused on
M. Fitzpatrick, Matthew R. Gingo, C. Kessinger, L. Lucht, E. Kleerup, R. Greenblatt, D. Claman, Claudia Ponath, S. Fong, Laurence Huang, A. Morris   +10 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Value of lung diffusing capacity for nitric oxide in systemic sclerosis

Physiological Reports, 2019
A decreased lung diffusing capacity for carbon monoxide (DLCO) in systemic sclerosis (SSc) is considered to reflect losses of alveolar membrane diffusive conductance for CO (DMCO), due to interstitial lung disease, and/or pulmonary capillary blood volume
Giovanni Barisione, Alessandro Garlaschi, Mariaelena Occhipinti, Michele Baroffio, Massimo Pistolesi, Vito Brusasco   +5 more
doaj   +1 more source

Diffusion Cocktail: Mixing Domain-Specific Diffusion Models for Diversified Image Generations [PDF]

arXiv, 2023
Diffusion models, capable of high-quality image generation, receive unparalleled popularity for their ease of extension. Active users have created a massive collection of domain-specific diffusion models by fine-tuning base models on self-collected datasets. Recent work has focused on improving a single diffusion model by uncovering semantic and visual
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertension

Respiratory Research, 2013
BackgroundReduced gas transfer in patients with pulmonary arterial hypertension (PAH) is traditionally attributed to remodeling and progressive loss of pulmonary arterial vasculature that results in decreased capillary blood volume available for gas ...
S. Farha, D. Laskowski, Deepa George, Margaret M. Park, W. Tang, R. Dweik, S. Erzurum   +6 more
semanticscholar   +1 more source

On the structure of diffuse measures for parabolic capacities

Comptes Rendus. Mathématique, 2019
Let $Q=(0,T)\times $, where $ $ is a bounded open subset of $\mathbb{R}^d$. We consider the parabolic $p$-capacity on $Q$ naturally associated with the usual $p$-Laplacian. Droniou, Porretta and Prignet have shown that if a bounded Radon measure $ $ on $Q$ is diffuse, i.e.
Andrzej Rozkosz, Tomasz Klimsiak
openaire   +3 more sources

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Impaired Carbon Monoxide Diffusing Capacity is the Strongest Predictor of Exercise Intolerance in COPD

COPD, 2013
Background: Exercise intolerance is a hallmark of chronic obstructive pulmonary disease (COPD) and forced expiratory volume in one second (FEV1) is the traditional metric used to define the severity of COPD.
A. Farkhooy, C. Janson, R. H. Arnardóttir, A. Malinovschi, M. Emtner, H. Hedenström   +5 more
semanticscholar   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source