Results 71 to 80 of about 3,622,504 (385)

Is Lymphopenia Detected in Sarcoidosis Associated with the Disease Activity?

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]The association of lymphopenia detected in patients with sarcoidosis with disease activity was investigated in the present study.[¤]METHODS[|]Patients who were diagnosed as having sarcoidosis and healthy volunteers/individuals with no ...
Coşkun Doğan, Sevda Şener Cömert, Benan Çağlayan, Elif Torun Parmaksız, Nesrin Kıral, Recep Demirhan, Ali Fidan, Seda Beyhan Sağmen   +7 more
doaj   +1 more source

Lung ultrasound in systemic sclerosis: correlation with high-resolution computed tomography, pulmonary function tests and clinical variables of disease [PDF]

, 2015
Interstitial lung disease (ILD) is a hallmark of systemic sclerosis (SSc). Although high-resolution computed tomography (HRCT) is the gold standard to diagnose ILD, recently lung ultrasound (LUS) has emerged in SSc patients as a new promising technique ...
Amoroso, Antonio, Barbano, Biagio, Barilaro, Giuseppe, Gigante, Antonietta, Giovannetti, Antonello, Lucci, Silvio, Quarta, Silvia, Rosato, Edoardo, ROSSI FANELLI, Filippo   +8 more
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Inflammation associated with lung function abnormalities in COVID-19 survivors

BMC Pulmonary Medicine, 2023
Background Activation of inflammatory pathways promotes organ dysfunction in COVID-19. Currently, there are reports describing lung function abnormalities in COVID-19 survivors; however, the biological mechanisms remain unknown. The aim of this study was
Roberto Mancilla-Ceballos, Kathryn M. Milne, Jordan A. Guenette, Arturo Cortes-Telles   +3 more
doaj   +1 more source

Role of single-breath diffusing capacity for carbon monoxide in patients with chronic obstructive pulmonary disease

Al-Azhar Assiut Medical Journal, 2021
Background Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities, usually caused by ...
Hamdy M Abd-Allah, Hytham Abdalla, Shazly Ahmed, Mahmoud H Mohammed   +3 more
doaj   +1 more source

The Single-Breath Diffusing Capacity of CO and NO in Healthy Children of European Descent

PLoS ONE, 2014
Rationale The diffusing capacity (DL) of the lung can be divided into two components: the diffusing capacity of the alveolar membrane (Dm) and the pulmonary capillary volume (Vc).
Astrid Thomas, B. Hanel, J. Marott, F. Buchvald, J. Mortensen, K. Nielsen   +5 more
semanticscholar   +1 more source

Small atom diffusion and breakdown of the Stokes–Einstein relation in the supercooled liquid state of the Zr46.7Ti8.3Cu7.5Ni10Be27.5 alloy [PDF]

, 1996
Be diffusivity data in the bulk metallic glass forming alloy Zr46.7Ti8.3Cu7.5Ni10Be27.5 are reported for temperatures between 530 and 710 K, extending 85 K into the supercooled liquid state of the alloy.
Geyer, U., Johnson, W. L., Macht, M.-P., Qiu, Y., Schneider, S., Tombrello, T. A.   +5 more
core   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Development and validity testing of an IPF-specific version of the St George's Respiratory Questionnaire [PDF]

, 2010
Rationale The St George's Respiratory Questionnaire (SGRQ) is often applied to assess health-related quality of life in patients with idiopathic pulmonary fibrosis (IPF). Some SGRQ items will inevitably have weaker measurement properties than others when
Jones, PW, Swigris, JJ, Yorke, J
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source