Results 81 to 90 of about 30,853 (284)
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Functional Significance of a Low Pulmonary Diffusing Capacity for Carbon Monoxide* [PDF]
, 1965 Robert L. Johnson +2 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Quantitative morphology of compensatory lung growth
European Respiratory Review, 2006 Compensatory lung growth is defined by the absolute increases in the quantity of functioning lung tissue in response to injury and/or disease, leading to a positive impact on functional outcome. The pneumonectomy model is used as an example to illustrate
C. C. W. Hsia
doaj
Arthritis Research & Therapy, 2019 Background Previous studies have shown the relationship between higher skin thickness score and the existence of organ involvements in systemic sclerosis (SSc).
Kazuki M. Matsuda +11 more
doaj +1 more source
Diffusing capacity, specific diffusing capacity and interpretation of diffusion defects.
The Western journal of medicine, 1976 Six pathophysiologic mechanisms of a reduced single breath CO diffusing capacity are discussed and the usefulness of relating carbon monoxide (CO) uptake to the functioning alveolar volume (DL/VA, specific diffusing capacity) is illustrated for several pulmonary diseases.
L N, Ayers +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
Effect of lung inflation on pulmonary diffusing capacity at rest and exercise. [PDF]
, 1966 John M. Miller, Robert L. Johnson
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
STUDIES OF RESPIRATORY PHYSIOLOGY IN CHILDREN. VI. LUNG DIFFUSING CAPACITY, DIFFUSING CAPACITY OF THE PULMONARY MEMBRANE AND PULMONARY CAPILLARY BLOOD VOLUME IN CONGENITAL HEART DISEASE* [PDF]
, 1961 Giovanni Bucci, Charles D. Cook
openalex +1 more source