Results 51 to 60 of about 2,937,719 (310)

Microstructure and strengthening mechanism of diffusion bonding joints of 6063 aluminum alloy under the monomolecular surface protection of α-terpineol

Journal of Materials Research and Technology
6063 aluminum alloy is often used in the manufacture of microchannel heat exchangers, which are formed by diffusion bonding to connect laminates, and diffusion bonding is a key technology that determines the production quality.
Jiafen Song, Lichi Ma, Shiming Xu, Yu Peng, Jiangtao Xiong, Jinglong Li   +5 more
doaj   +1 more source

Microstructural Evolution in Nonvacuum Solid-State Diffusion Bonded Joints of AA2219

Advances in Materials Science and Engineering, 2023
Solid-state diffusion bonding of AA2219 alloy is carried out under the nonvacuum condition to form AA2219/AA2219 joints. In the currently adopted method, AA2219 alloys are joined under the bonding temperature of 450–500°C, bonding pressure of 10 MPa, and
Manjunath Vatnalmath, V. Auradi, V. Bharath, Madeva Nagaral, N. Nagaraj, A. Haiter Lenin   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Corrosion Behavior of Diffusion Bonding Joints of (OFHC) Copper with Stainless Steel 304L in 3.5% NaCl

مجلة النهرين للعلوم الهندسية, 2018
The present work deals with direct diffusion bonding welding without interlayer of austenitic stainless steel type AISI 304L with Oxygen Free High Conductivity pure copper (OFHC) in vacuum atmosphere (1.5 *10-5 mbr.).
Sami Abualnoun Ajeel, Ahmed Ali Akbar Akbar, Safaa Mohammed Hassoni   +2 more
doaj   +1 more source

Computational Study on Surface Bonding Based on Nanocone Arrays

Nanomaterials, 2021
Surface bonding is an essential step in device manufacturing and assembly, providing mechanical support, heat transfer, and electrical integration. Molecular dynamics simulations of surface bonding and debonding failure of copper nanocones are conducted ...
Xiaohui Song, Shunli Wu, Rui Zhang
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Diffusion Bonding of Molybdenum

Journal of the Japan Welding Society, 1968
It is generally acknowledged that the ductile joint of molybdenum is difficult to make by fusion welding because of its embrittleness due to recrystallization and grain growth.The purpose of this investigation is to obtain a ductile joint of pure molybdenum without recrystallization and extreme deformation by diffusion or pressure bonding processes ...
Hashimoto, Tatsuya, Tanuma, Kinji
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source