Results 31 to 40 of about 6,599 (190)

Diffusion kurtosis and quantitative susceptibility mapping MRI are sensitive to structural abnormalities in amyotrophic lateral sclerosis

open access: yesNeuroImage: Clinical, 2019
Objective: To construct a clinical diagnostic biomarker using state-of-the-art microstructural MRI in the motor cortex of people with amyotrophic lateral sclerosis (ALS).
Thomas Welton   +5 more
doaj   +1 more source

Diffusion Kurtosis Imaging of Neonatal Spinal Cord in Clinical Routine [PDF]

open access: yesFrontiers in Radiology, 2021
Diffusion kurtosis imaging (DKI) has undisputed advantages over the more classical diffusion magnetic resonance imaging (dMRI) as witnessed by the fast-increasing number of clinical applications and software packages widely adopted in brain imaging. However, in the neonatal setting, DKI is still largely underutilized, in particular in spinal cord (SC ...
Rosella Trò   +11 more
openaire   +4 more sources

Investigating the relationship between diffusion kurtosis tensor imaging (DKTI) and histology within the normal human brain

open access: yesScientific Reports, 2021
Measurements of water diffusion with MRI have been used as a biomarker of tissue microstructure and heterogeneity. In this study, diffusion kurtosis tensor imaging (DKTI) of the brain was undertaken in 10 healthy volunteers at a clinical field strength ...
Ahmed Maiter   +11 more
doaj   +1 more source

Combined Application of Quantitative Susceptibility Mapping and Diffusion Kurtosis Imaging Techniques to Investigate the Effect of Iron Deposition on Microstructural Changes in the Brain in Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2022
ObjectivesBrain iron deposition and microstructural changes in brain tissue are associated with Parkinson’s disease (PD). However, the correlation between these factors in Parkinson’s disease has been little studied.
Lin Yang   +12 more
doaj   +1 more source

Fast diffusion kurtosis imaging of fibrotic mouse kidneys [PDF]

open access: yesNMR in Biomedicine, 2016
Diffusion kurtosis imaging (DKI) is sensitive to tissue microstructure and may therefore be useful in the diagnosis and monitoring of disease in brain and body organs. Generally, diffusion magnetic resonance imaging (dMRI) in the body is challenging because of the heterogeneous body composition, which can cause image artefacts as a result of chemical ...
Kjølby, Birgitte Fuglsang   +10 more
openaire   +3 more sources

Application of diffusion kurtosis imaging in neonatal brain development

open access: yesFrontiers in Pediatrics, 2023
BackgroundDeviations from the regular pattern of growth and development could lead to early childhood diseases, suggesting the importance of evaluating early brain development. Through this study, we aimed to explore the changing patterns of white matter and gray matter during neonatal brain development using diffusion kurtosis imaging (DKI).Materials ...
Xueyuan Wang   +10 more
openaire   +3 more sources

Spatially selective 2D RF inner field of view (iFOV) diffusion kurtosis imaging (DKI) of the pediatric spinal cord

open access: yesNeuroImage: Clinical, 2016
Magnetic resonance based diffusion imaging has been gaining more utility and clinical relevance over the past decade. Using conventional echo planar techniques, it is possible to acquire and characterize water diffusion within the central nervous system (
Chris J. Conklin   +11 more
doaj   +1 more source

Temporal lobe microstructural abnormalities in patients with nasopharyngeal carcinoma quantitatively evaluated by high-resolution DWI and DKI after concurrent chemoradiotherapy

open access: yesClinical and Translational Radiation Oncology, 2020
Purpose: To investigate temporal lobe microstructural abnormalities and neurocognitive function impairment after concurrent chemoradiotherapy (CCRT) in patients with nasopharyngeal carcinoma (NPC).
Gang Wu   +6 more
doaj   +1 more source

Diffusion kurtosis imaging of gray matter in schizophrenia

open access: yesCortex, 2019
Prior postmortem studies have shown gray matter (GM) microstructural abnormalities in schizophrenia. However, few studies to date have examined GM microstructural integrity in schizophrenia in vivo. Here, we employed diffusion kurtosis imaging (DKI) to test for differences in GM microstructure in eighteen schizophrenia (SZ) patients versus nineteen ...
Faye F. McKenna   +4 more
openaire   +3 more sources

Fast imaging of mean, axial and radial diffusion kurtosis [PDF]

open access: yesNeuroImage, 2016
Diffusion kurtosis imaging (DKI) is being increasingly reported to provide sensitive biomarkers of subtle changes in tissue microstructure. However, DKI also imposes larger data requirements than diffusion tensor imaging (DTI), hence, the widespread adaptation and exploration of DKI would benefit from more efficient acquisition and computational ...
Brian Hansen   +2 more
openaire   +3 more sources

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