Results 81 to 90 of about 8,073,665 (296)
From Pixels to Precision: Generative Artificial Intelligence as a Paradigm Shift in Spine Imaging—Technical Foundations, Clinical Applications, and the Path to Safe Clinical Deployment [PDF]
NeurospineSpine imaging represents a complex diagnostic frontier characterized by anatomical variability, motion artifacts, metallic instrumentation interference, and significant inter-reader diagnostic variability (κ=0.20 across institutions).
Daniyal Ashraf +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Progressive Disease Image Generation with Ordinal-Aware Diffusion Models
DiagnosticsBackground/Objectives: Ulcerative Colitis (UC) lacks longitudinal visual data, which limits both disease progression modeling and the effectiveness of computer-aided diagnosis systems.
Meryem Mine Kurt +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cube-based diffusion algorithm [PDF]
, 2007 We study molecular diffusion in (linear) nanopores with different types of roughness in the so-called Knudsen regime. Knudsen diffusion represents the limiting case of molecular diffusion in pores, where mutual encounters of the molecules within the free
Kärger, Jörg +3 more
core +1 more source
Exploring the Mathematical Foundations of Generative AI Models: VAEs, GANs, Transformers, and DMs
IEEE AccessGenerative Artificial Intelligence (GAI) has rapidly advanced, revolutionizing content creation across diverse domains, including text, image, audio, and video synthesis.
Sivarama Prasad Tera +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
IEEE Open Journal of Engineering in Medicine and BiologyGoal: To accurately detect infections in Diabetic Foot Ulcers (DFUs) using photographs taken at the Point of Care (POC). Achieving high performance is critical for preventing complications and amputations, as well as minimizing unnecessary emergency ...
Palawat Busaranuvong +6 more
doaj +1 more source
Time-efficient Diffusion Models for Semantic Segmentation of Choroid Plexus from brain MRI [PDF]
openSince their introduction, diffusion models have achieved significant success in various applications, demonstrating superiority over other generative models.
GIUPPONI, ALESSANDRO
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source