Results 111 to 120 of about 197,383 (292)

The application of low crude protein wheat-soyabean diets to growing and finishing pigs: 2. The effects on nutrient digestibility, nitrogen excretion, faecal volatile fatty acid concentration and ammonia emission from boars [PDF]

, 2005
peer-reviewedThis study received financial support from Telltech Ltd. (Wicklow, Ireland) and Enterprise Ireland (Dublin, Ireland).Diets containing 132, 152, 183 and 206 g/kg crude protein (CP) were fed to growing and finishing boars to evaluate the ...
Callan, J.J., Henry, R. W., Leek, A. B. G., O'Doherty, John V.   +3 more
core  

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Evaluation of feed digestibility in goats based on palm oil industry waste and fisheries in Southwest Papua

Jurnal Ilmu Peternakan Terapan
Palm oil and fishery waste are recognized as potential environmental concerns, necessitating their processing for reuse as feed material. This study aimed to evaluate the digestibility of feed materials based on palm oil waste and fish waste, utilizing ...
Andi Wijaya, Rizal Aditama, Sri Firman, Reza Puspitasari, Alfian Duwith, Antonius Iba   +5 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

The Effects of Different Energy and Protein Ratio to Goat’s Nutrient Intake and Digestibility

, 2013
The objective of this research was to study the effects of different energy and protein ratio towards goat’s nutrient intake and digestibility. Twenty four male goats, 6 – 7 months old with initial average live weight 13+1.56 kg, coefficient variant11 ...
Agung, Purnomoadi, S., Soedarsono, S., Sunarso, Sri, Mawati   +3 more
core  

Effects of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers [PDF]

, 2007
peer-reviewedThe objective of this experiment was to investigate the effects and interactions of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers.
Cummins, B., Keane, Michael G., Kenny, David A., O'Kiely, Padraig   +3 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cooking shapes the structure and function of the gut microbiome [PDF]

, 2019
Diet is a critical determinant of variation in gut microbial structure and function, outweighing even host genetics1-3. Numerous microbiome studies have compared diets with divergent ingredients1-5, but the everyday practice of cooking remains ...
Turnbaugh, Peter
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source