Results 91 to 100 of about 128,850 (286)

Pulsed electric field (PEF) processing of microalga Chlorella vulgaris and its digestibility in broiler feed

open access: yesPoultry Science
: Microalgae have potentially beneficial effects on animal health and nutritional value when added to feed. Crucial hereby is that intracellular bio-active molecules are released in the intestinal tract. Digestibility of Chlorella vulgaris and its impact
Sofie Van Nerom   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Digestibility of feeds in fish and shellfish and methods to determine digestibility [PDF]

open access: yes, 1987
Digestibility of a feedstuff can be described as the amount of feed that can be digested and absorbed by the animal in relation to consumption.
Vijayakumaran, M
core   +1 more source

Factors influencing the total tract apparent digestibility of nutrients from wheat for the weanling pig [PDF]

open access: yes, 2003
The objectives of the studies conducted in the Part A of this thesis were to quantify the variation of digestible energy (DE) content of wheat and to document the responsible factors for the variation.
Kim, Jae Cheol
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The pig is an excellent model to determine amino acid digestibility of human foods and to generate data needed to meet human amino acid requirements

open access: yesFrontiers in Nutrition
The protein value of any food item is determined by the quantity and ileal digestibility of indispensable amino acids in that food. To determine the ileal digestibility of amino acids, an animal model needs to be used, and the pig is the preferred model ...
Hans H. Stein
doaj   +1 more source

Modifying crops to increase cell wall digestibility [PDF]

open access: yes, 2012
Improving digestibility of roughage cell walls will improve ruminant animal performance and reduce loss of nutrients to the environment. The main digestibility impediment for dicotyledonous plants is highly lignified secondary cell walls, notably in stem
Deborah A. Samac   +5 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A new in vitro method to evaluate digestibility of commercial diets for dogs

open access: yesItalian Journal of Animal Science, 2016
The aim of the present study was to develop a new in vitro method for evaluating the digestibility of commercial diets for dogs. First, in order to develop the in vitro method, the digestibility of four commercial diets for dogs was evaluated through ...
Giacomo Biagi   +5 more
doaj   +1 more source

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