Results 41 to 50 of about 496,317 (381)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
The use of near infrared reflectance spectroscopy (NIRS) for prediction of the nutritive value of barley for growing pigs [PDF]
peer-reviewedThere is a need in the feed industry for a rapid means of evaluating the nutritive value of feeds and feed ingredients. Chemical analysis provides only basic information and most of the laboratory techniques take too long for this ...
Agnew, R.E.+2 more
core
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Digestibility and nutrient utilisation of soybean bran-based diets in Nile tilapia Oreochromis niloticus [PDF]
The digestibility and utilisation of two soybean bran-based diets and two fishmeal-based diets serving as control, at optimal (30%) and suboptimal (20%) protein levels were evaluated in Oreochromis niloticus.
Alao, I.A.+2 more
core
Multi-scale structure, pasting and digestibility of adlay (Coixlachryma-jobi L.) seed starch [PDF]
peer-reviewedThe hierarchical structure, pasting and digestibility of adlay seed starch (ASS) were investigated compared with maize starch (MS) and potato starch (PS).
Chen, Jicheng+5 more
core +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Brown Mid-Rib Corn Variety Trial [PDF]
Brown mid-rib (BMR) corn has a lower lignin content than other silage corn varieties. The lower lignin content increases the fiber digestibility (NDF digestibility) of the corn silage. Increases in NDF digestibility lead to increased in dry matter intake,
Burke, Conner+5 more
core +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Growing attention is being directed toward insects as a novel and sustainable source of protein for pet food. The aim of the study was to evaluate nutrient digestibility of a diet containing black soldier fly larvae as its main protein source.
Livio Penazzi+11 more
doaj +1 more source