Results 101 to 110 of about 3,272 (311)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Microwave enhanced digestion of aerobic SBR sludge

open access: yesWater SA, 2009
Factorial experiments were carried out to determine the potential of microwaves (MWs) for improving characteristics of aerobic sequencing batch reactor (SBR) sludge to enhance mesophilic anaerobic digestion. Effects of pretreatment temperature, MW irradiation intensity and solids concentration on sludge characterisation parameters were monitored ...
Kennedy, KJ, Thibault, G, Droste, RL
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of 6‐phytase produced with Trichoderma reesei (CBS 126897) (Quantum® Blue) for fin fish (ROAL Oy)

open access: yesEFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 6‐phytase (Quantum® Blue) as a zootechnical feed additive for fin fish. The additive is authorised for use in poultry and pigs.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +28 more
doaj   +1 more source

Safety and efficacy of OPTIPHOS® (6‐phytase) as a feed additive for finfish

open access: yesEFSA Journal, 2017
The additive OPTIPHOS® is a preparation of 6‐phytase that is authorised for use in avian species, weaned piglets, pigs for fattening and sows. The applicant seeks for an extension of use of the product to finfish, at a dose range between 250 and 1,000 ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +24 more
doaj   +1 more source

Cinnamaldehyde enhances in vitro parameters of immunity and reduces in vivo infection against avian coccidiosis [PDF]

open access: yes, 2017
The effects of cinnamaldehyde (CINN) on in vitro parameters of immunity and in vivo protection against avian coccidiosis were evaluated. In vitro stimulation of chicken spleen lymphocytes with CINN (25-400ng/ml) induced greater cell proliferation ...
Bravo, David   +6 more
core  

Isolation of structurally distinct lignin–carbohydrate fractions from maize stem by sequential alkaline extractions and endoglucanase treatment [PDF]

open access: yes, 2013
Sequential fractionation of extractive-free maize stems was carried out using two mild alkaline extractions (0.5 and 2 M NaOH, 20 'C, 24 h) before and after endoglucanase treatment.
Baumberger, Stéphanie   +3 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The effects of different levels of biogen probiotic additives on growth indices and body composition of juvenile common carp (Cyprinus carpio L.) [PDF]

open access: yes, 2012
An experiment was conducted to evaluate the effects of biogen probiotic additives on growth performance of common carp, Cyprinus carpio. Four practical diets containing 0 (control) , 0.1, 0.2 and 0.3 % Biogen probiotic were used to feed fish. Seventy-two
Nasrollahzadeh, A., Noveirian, H.A.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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