Results 81 to 90 of about 103,599 (300)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 2022 Additional file 1: Supplementary Information. Figure S1. Supplemental ARID1A knockdown differential H3.3 data. Figure S2. H3.3 knockdown functional analysis. Figure S3. Effects of CHD4 loss on H3.3 chromatin and comparison to ARID1A.
Scott B. Rothbart (1616755) +10 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Erythrina foliage as an alternative feed for growing goats in Lao PDR [PDF]
, 2012 Foliages from some tropical plants and from different species of the legume Erythrina were examined in five studies assessing the characteristics of these foliages as feed for goats.
Kongmanila, Daovy
core +1 more source
EFSA Journal, 2020 Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of APSA PHYTAFEED® 20,000 GR/L (6‐phytase) as a ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
doaj +1 more source
Enhancers of eight Gossypium species.
, 2021 Enhancers of eight Gossypium ...
Jianying Li (9426689)
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The summary of the overlap between the predicted enhancers and the FANTOM5 enhancers.
, 2016 The summary of the overlap between the predicted enhancers and the FANTOM5 enhancers.
Yang Dai (36730) +2 more
core +1 more source
Validation using PacBio SVs and disease enhancers.
, 2020 a) Cumulative distribution function for LoF-tolerant scores for disease enhancers (red), all tested enhancers (grey), PacBio deleted enhancers (blue). KS-test P-values are between disease enhancers vs. all tested and PacBio enhancers vs. all tested.
Ekta Khurana (386863) +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source