Results 51 to 60 of about 114,401,429 (299)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Co-digestion of source segregated domestic food waste to improve process stability [PDF]

, 2012
Cattle slurry and card packaging were used to improve the operational stability of food waste digestion, with the aim of reducing digestate total ammoniacal nitrogen concentrations compared to food waste only.
Zhang, Yue, Banks, Charles J., Heaven, Sonia   +2 more
core   +1 more source

Lemon Balm as a Source of Potentially Bioaccessible Rosmarinic Acid: The Effect of Herbal Preparation Type, Dosage, and Digestion-Related Factors

Applied Sciences
This study aimed to evaluate how the dosage, type of herbal preparation (plant material, dry extract, or isolated compound), along with simulated digestion-related factors, i.e., digestion stage (gastric vs.
Łukasz Sęczyk
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Formation of Carcinogens in Processed Meat and Its Measurement with the Usage of Artificial Digestion—A Review

Molecules, 2022
Meat is a rich source of various nutrients. However, it needs processing before consumption, what in turn generates formation of carcinogenic compounds, i.a., polycyclic aromatic hydrocarbons (PAH), nitrosamines (NOCs), and the most mutagenic ...
Ewelina Pogorzelska-Nowicka, Marcin Kurek, Monika Hanula, Agnieszka Wierzbicka, Andrzej Półtorak   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Avaliação in vitro da eficiência de inóculos no tratamento anaeróbio de efluentes líquidos de suinocultura Efficiency of seeding material in anaerobic treatment of swine liquid waste: an in vitro trial

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
Avaliou-se o efeito de inóculos (tratamentos) na degradação dos dejetos líquidos de suínos, em diferentes tempos de detenção hidráulica (0, 30, 60, 90, 120, 150, 180 horas). Foram utilizados um inóculo comercial, na dose recomendada pelo fabricante, três
L.S. Rodrigues, I.J. Silva, P.R. Oliveira, C.M.M. Campos, F.L. Silva   +4 more
doaj   +1 more source

Development of an in vitro protein digestibility assay mimicking the chicken digestive tract

Animal Nutrition, 2018
It is difficult to obtain in vivo digestion kinetics data of high protein ingredients using chickens. Collecting kinetics data requires repeated sampling of digesta from the small intestine during the digestion process, which is not easily accomplished due to the anatomical structure of chicken digestive tract.
Dervan D.S.L. Bryan, Dawn A. Abbott, Henry L. Classen   +2 more
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Comparação do sistema de monitoramento computadorizado de digestão in vitro com os métodos in vivo e in situ: 2. Uso do resíduo da matéria seca de forragens Comparison of the in vitro digestion computerized monitoring system with in vivo and in situ methods: 2. Use of the dry matter residue of the forages

Revista Brasileira de Zootecnia, 2000
RESUMO - O objetivo deste trabalho foi comparar o sistema de monitoramento computadorizado da produção de gás in vitro com os métodos in vivo e in situ.
Fábio Prudêncio de Campos, Max Lázaro Vieira Bose, Celso Boin, Dante Pazzanese Duarte Lanna, Jozivaldo Prudêncio Gomes de Morais   +4 more
doaj   +1 more source