Results 111 to 120 of about 22,831,370 (389)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Identification of specific B cell linear epitopes of mycoplasma hyorhinis P37 protein using monoclonal antibodies against baculovirus-expressed P37 protein

open access: yesBMC Microbiology, 2019
Background Mycoplasma hyorhinis (Mhr) is the etiologic agent of lameness and polyserositis in swine. P37 is a membrane protein of Mhr that may be an important immunogen and is a potential target for diagnostic development.
Hongzhen Zhu   +8 more
doaj   +1 more source

The nose and tongue as chemical detectors

open access: yes, 2005
Human chemical senses are the gatekeepers of our digestive system. Chemical separation combined with human sensory perception has been used to isolate and identify a natural non-steroidal anti-inflammatory compound in olive oil.
Keast, Russell
core  

Pengembangan Media Video Animasi Digestive System untuk Meningkatkan Hasil Belajar Siswa Mata Pelajaran IPA Kelas V [PDF]

open access: yes, 2018
Siswa kesulitan dalam memahami materi IPA khususnya materi sistem pencernaan makanan pada manusia. Tujuan dari penelitian ini yaitu untuk mengetahui tingkat pemahaman konsep belajar siswa, memotivasi belajar siswa, serta untuk mengetahui hasil kelayakan ...
JANNAH, M. (MIFTACHUL)   +1 more
core  

Effects of Ingestion of Lithic Particles on Growth of the Apple Snail Pomacea canaliculata (Caenogastropoda, Ampullariidae) [PDF]

open access: yes, 2016
Lithic particles are a common feature in the digestive tract of freshwater snails. Their role in the digestive processes has been demonstrated in some microphytophagous and detritivorous species, as they enhance growth, assimilation and reproduction.
Manara, Enzo   +2 more
core   +1 more source

Immune Checkpoint Markers in Neuroendocrine Carcinoma of the Digestive System

open access: yesFrontiers in Oncology, 2020
Digestive system neuroendocrine carcinomas (NECs) are rare neoplasms originating from neuroendocrine cells with a poor prognosis and limited effective treatments.
Jiazhang Xing   +8 more
semanticscholar   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Development of Guided Inquiry Based Modules on Digestive System Materials to Increase Students' Science Process Skill [PDF]

open access: yes, 2015
The purpose of this research are : (1) to know the characteristics of modules based guided-inquiry development in food digestive system material to increase KPS, (2) to know the feasibility of modules based guided-inquiry development in food digestive ...
Prayitno, S. B. (Sugiyarto)   +1 more
core  

The Regulatory Functions of Circular RNAs in Digestive System Cancers

open access: yesCancers, 2020
Circular ribonucleic acids (circRNAs), which are a type of covalently closed circular RNA, are receiving increasing attention. An increasing amount of evidence suggests that circRNAs are involved in the biogenesis and development of multiple diseases ...
Xiao Yuan   +7 more
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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