Results 131 to 140 of about 22,831,370 (389)
Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]
Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L.+2 more
core
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Xiaohong Lu, Yuanjie Yu & Shiyun Tan (2019) Long non-coding XIAP-AS1 regulates cell proliferation, invasion and cell ...
Xiaohong Lu, Yuanjie Yu, Shiyun Tan
doaj +1 more source
Pleiotropic and Novel Phenotypes in The \u3cem\u3eDrosophila\u3c/em\u3e Gut Caused by Mutation of \u3cem\u3eDrop-Dead\u3c/em\u3e [PDF]
Normal gut function is vital for animal survival, and deviations from such function can contribute to malnutrition, inflammation, increased susceptibility to pathogens, diabetes, neurodegenerative diseases, and cancer.
Benske, Anika+6 more
core +1 more source
The composition of phosphate granules in the digestive glands of marine prosobranch gastropods: variation in relation to taxonomy [PDF]
The composition of some 1150 phosphate granules in the digestive glands of over 40 species of marine prosobranch gastropods has been surveyed using a simple preparation technique and semiquantitative SEM x-ray microanalysis. Spectral peaks for Mg, K, Ca,
Bebianno, Maria João+3 more
core +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou+5 more
wiley +1 more source
Students' understandings of human organs and organ systems [PDF]
How do people develop their understanding of what is inside them? This study looks at students' understandings of their internal structure. A cross-sectional approach was used involving a total of 158 students in England from six different age groups ...
Reiss, Michael, Tunnicliffe, Sue Dale
core +2 more sources
Biofloc technology application in aquaculture to support sustainable development goals [PDF]
Biofloc technology (BFT) application offers benefits in improving aquaculture production that could contribute to the achievement of sustainable development goals.
Bossier, Peter, Ekasari, Julie
core +2 more sources
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban+12 more
wiley +1 more source