Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla +36 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Penerapan Model Pembelajaran Kooperatif Tipe Numbereded Heads Together (NHT) pada Konsep Sistem Pencernaan Makanan pada Manusia di Kelas IV SD Negeri Mandalasari 1 Kecamatan Puspahiang Kabupaten Tasikmalaya. [PDF]
Research aims to understand match / the accuracy of learning model cooperative type Numbered heads & together ( nht in learning the concept of digestive system food on human beings in fourth grade land mandalasari 1 kecamatan puspahiang the market.
Nuryadin, E. (Egi)
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ObjectiveOur study represents the first meta-analysis conducted to evaluate the prognostic utility of the baseline prognostic nutritional index (PNI) in patients with gastrointestinal cancer (GIC) who received immune checkpoint inhibitor (ICI) therapy ...
Lilong Zhang +13 more
doaj +1 more source
Glycocalyx production in teleosts [Translation from: Verhandlungen der Deutschen Zoologischen Gesellschaft, p.286, 1970] [PDF]
Shielding the organism against harmful effects from the environment is one of the most important tasks of the outer covering of all animals. The epidermis of primarily aquatic organisms and the epithelia of organs which are exposed to water, such as the ...
Bereiter-Hahn, J., Schwerdtfeger, W. K.
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Special Chimeric Antigen Receptor (CAR) Modifications of T Cells: A Review
Chimeric antigen receptor (CAR) -T cell therapy has become one of the hot topics in tumor immunity research in recent years. Although CAR-T cell therapy is highly effective in treating hematological malignancies, there are numerous obstacles that prevent
Lele Miao +14 more
doaj +1 more source
Outreach Education: Making Neuroscience Readily Available for Rural Students and Communities of Alaska [PDF]
WHAT is neuroscience? Neuroscience is the scientific study of the structure or function of the nervous system and brain. To get a grasp on the vast study of neuroscience, first think of the human body and how complex it is. Think of the skeletal system
Ellison, Ariel
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

