Results 41 to 50 of about 733,462 (310)
Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies
Systematic Reviews, 2022 Background and objectives Cancer morbidity and mortality rates remain high, and thus, at present, considerable efforts are focused on finding drugs with higher sensitivity against tumor cells and fewer side effects. Disulfiram (DSF), as an anti-alcoholic
Ling Wang +4 more
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CONTROLLING KIDNEY WORMS IN SWINE IN THE SOUTHERN STATES [PDF]
, 1934 The kidney worm of swine is one of the most serious obstacles to profitable swine. production in the. South.. Since these parasites are located in the liver, kidney fat, kidney tissue proper, blood vessels, and other parts of the body outside the ...
Schwartz, Benjamin
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GDNF‐RET signaling drives pulmonary neuroendocrine cell hyperplasia and allergic airway inflammation
FEBS Letters, EarlyView.A neuroimmune interaction centered on the PNEC‐ILC2 axis in an asthma model. PNEC‐derived CGRP activates nearby ILC2s, which then release cytokines, including IL‐5 and IL‐13. These cytokines promote eosinophil and macrophage infiltration. Subsequently, GDNF produced by these cells induces PNEC hyperplasia via the GDNF receptors, RET and GFRα1 ...
Tasuku Kawano +3 more
wiley +1 more source
Case Reports in Gastrointestinal Medicine, 2011 We report the first known case of a retroperitoneal leiomyosarcoma that presented with an endoscopically defined source of gastrointestinal bleeding in the colon. A 68-year-old male with a history of diverticulosis, hypertension, and hypercholesterolemia
Dominic G. Ventura +2 more
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Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. [PDF]
, 2017 During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained
Darbellay, Fabrice +4 more
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Small mammals feeding on hypogeous fungi [PDF]
, 2014 The spores stay viable after passing through the animal gut, and in some cases their ability to germinate and form mycorrhiza is enhanced after leaving the intestine.
Połatyńska, Małgorzata
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Association of STMN1 with survival in solid tumors: A systematic review and meta-analysis
The International Journal of Biological Markers, 2019 Background: The prognostic value of Stathmin 1 (STMN1) in malignant solid tumors remains controversial. Thus, we conducted this meta-analysis to summarize the potential value of STMN1 as a biomarker for predicting overall survival in patients with solid ...
Dan Zhang +4 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Frontiers in Neurology, 2021 Objectives: To analyze the clinical and imaging features of acute ischemic stroke (AIS) related to gastrointestinal malignant tumor, and to explore the prognostic factors.Methods: Clinical data of consecutive patients with gastrointestinal malignant ...
Yating Liu +7 more
doaj +1 more source