Results 81 to 90 of about 25,425,556 (293)

Transcriptomic effects of the non-steroidal anti-inflammatory drug Ibuprofen in the marine bivalve Mytilus galloprovincialis Lam [PDF]

open access: yes, 2016
The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L-1) are presented. Using a 1.7 K feature cDNA microarray along with linear models
Amorim, Monica J. B.   +3 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Roles of the CXCL8-CXCR1/2 Axis in the Tumor Microenvironment and Immunotherapy

open access: yesMolecules, 2021
In humans, Interleukin-8 (IL-8 or CXCL8) is a granulocytic chemokine with multiple roles within the tumor microenvironment (TME), such as recruiting immunosuppressive cells to the tumor, increasing tumor angiogenesis, and promoting epithelial-to ...
Zhi-Jian Han   +5 more
doaj   +1 more source

Morphology and histology of the digestive gland of Oxychilus (Drouetia) atlanticus (Morelet & Drouët) (Gastropoda: Pulmonata). [PDF]

open access: yes, 2001
Little information exists on the histology of Zonitidae digestive system. This study deals with a detailed characterization of the different types of cells comprising epithelium lining the digestive gland of 0xychilus atlanticus.
Lopes, Marco   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Approaching treatment for immunological rejection of living-donor liver transplantation in rats

open access: yesBMC Gastroenterology, 2020
Background The anti-immunological rejection therapy for small-for-size syndrome (SFSS) after live donor liver transplantation (LDLT) play a central role in keeping graft survival.
Yanhu Feng   +12 more
doaj   +1 more source

Digestive system anatomy of the Acipenser persicus: New features [PDF]

open access: yes, 2013
Sturgeon is one of the most important species of the Caspian Sea aquatics. Unfortunately, this species faces the threat of extinction today. This makes specific studies on any type of sturgeons more important than before.
Akhtarzade, M.   +4 more
core  

Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]

open access: yes, 2018
Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R.   +3 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Liver Transplantation for Hepatocarcinoma: Results over Two Decades of a Transplantation Programme and Analysis of Factors Associated with Recurrence

open access: yesBiomedicines
Background: In recent years, many studies have attempted to develop models to predict the recurrence of hepatocarcinoma after liver transplantation.
María Martínez Burgos   +6 more
doaj   +1 more source

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