Results 81 to 90 of about 22,831,370 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Approaching treatment for immunological rejection of living-donor liver transplantation in rats

open access: yesBMC Gastroenterology, 2020
Background The anti-immunological rejection therapy for small-for-size syndrome (SFSS) after live donor liver transplantation (LDLT) play a central role in keeping graft survival.
Yanhu Feng   +12 more
doaj   +1 more source

Overexpressed PAQR4 predicts poor overall survival and construction of a prognostic nomogram based on PAQR family for hepatocellular carcinoma

open access: yesMathematical Biosciences and Engineering, 2022
Objective: We aimed to explore the expression and clinical prognostic significance of PAQR4 in hepatocellular carcinoma (HCC). Methods: We obtained the gene expression matrix and clinical data of HCC from the cancer genome atlas (TCGA) and ...
Caihao Qu   +4 more
doaj   +1 more source

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. [PDF]

open access: yes, 2017
During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained
Darbellay, Fabrice   +4 more
core   +1 more source

A Microarray study of Carpet-Shell Clam (Ruditapes decussatus) shows common and organ-specific growth-related gene expression Differences in gills and digestive gland [PDF]

open access: yes, 2017
Growth rate is one of the most important traits from the point of view of individual fitness and commercial production in mollusks, but its molecular and physiological basis is poorly known.
Carlos Saavedra   +7 more
core   +3 more sources

Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida - A Comparative Study [PDF]

open access: yes, 2020
The fruits of some Cornus species (dogwoods) are used in traditional medicine and considered potential anti-diabetic and hypolipemic agents. The aim of the study was to determine the ability of extracts from Cornus alba (CA), Cornus florida (CF), and ...
Buchholz, Tina   +7 more
core   +1 more source

Diagnosis of digestive system tumours

open access: yesInternational Journal of Cancer, 2020
The WHO Classification of Tumours provides the international standards for the classification and diagnosis of tumours. It enables direct comparisons to be made between different countries.
M. Washington   +15 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

CONTROLLING KIDNEY WORMS IN SWINE IN THE SOUTHERN STATES [PDF]

open access: yes, 1934
The kidney worm of swine is one of the most serious obstacles to profitable swine. production in the. South.. Since these parasites are located in the liver, kidney fat, kidney tissue proper, blood vessels, and other parts of the body outside the ...
Schwartz, Benjamin
core   +1 more source

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