Results 51 to 60 of about 1,144,886 (364)
Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]
, 2018 Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R. +3 more
core +2 more sources
Cholelithiasis as a possible manifestation of systemic digestive diseases
Terapevticheskii arkhiv, 2015 To comprehensively study of the function of digestive organs in cholelithiasis (CL).Three hundred and seventeen patients with the early (prestone) stage of CL were examined. The latter was verified by ultrasonography (USG) and biochemical bile tests. The patients underwent pH metry and esophagogastroduodenoscopy, followed by histological examination of
M V Lyapina +5 more
openaire +4 more sources
SLAS Discovery, 2022 Background: Kaposi's sarcoma-associated herpes virus (KSHV) initiate and accelerate the development of Kaposi's sarcoma (KS), and KSHV possesses many cancer-associated genes, including KSHV-derived microRNA miR-K12–1, which has been identified to be ...
Xiaoling Huang +9 more
doaj
Potential role of irisin in digestive system diseases
Biomedicine & Pharmacotherapy, 2023 Digestive system diseases (DSD) are very complex conditions that severely threaten human health. Therefore, there is an urgent need to develop new pharmacological treatment strategies. Irisin, a myokine discovered in 2012, is produced by fibronectin type III domain-containing protein 5 (FNDC5), which is a transmembrane protein.
Yueming Zhang +4 more
openaire +2 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
The substrate of the biopsychosocial influences in the carcinogenesis of the digestive tract [PDF]
, 2016 Digestive cancer represents a severe public health problem, being one of the main causes of death. It is considered a multifactorial disease, with hereditary predisposition, environmental factors, and other factors involved in carcinogenesis.
Caragea, Daniel +5 more
core +5 more sources
DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks. [PDF]
, 2018 Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability.
Chen, Hongping +21 more
core +2 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Diseases of the digestive system
Kazan medical journal, 1934 In the preface to his book, Prof. R.A. Luria writes: "Diseases of the digestive organs are undoubtedly the most frequent diseases with which the therapist has to deal. It is impossible not to agree with this, as well as with the idea that this area of internal medicine is the least familiar to a wide range of physicians.
openaire +2 more sources