Results 81 to 90 of about 1,487,193 (321)

Common molecular basis for MASH and hepatitis C revealed via systems biology approach

Frontiers in Oncology
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by liver inflammation and damage caused by a buildup of fat in the liver.
Yongwei Cheng, Zihao Song, Ye Liu, Xichao Xu, Dali Zhang, Yigui Zou, Liang Liu, Yinzhen Zeng, Wenwen Li, Daming Bai, Dongling Dai   +10 more
doaj   +1 more source

Digestive diseases of cattle diagnosed at the “Clínica de Bovinos de Garanhuns”-UFRPE: retrospective study and influence of seasonality

Pesquisa Veterinária Brasileira, 2021
: Diseases of the bovine digestive system make up an important group of diseases, often being responsible for significant economic losses in the livestock sector.
Gliére S.L. Soares, Nivaldo A. Costa, José Augusto B. Afonso, Maria I. Souza, Jobson F.P. Cajueiro, Jean C.R. Silva, Fernando Ferreira, Carla L. Mendonça   +7 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Digestive system involvement of novel coronavirus infection: Prevention and control infection from a gastroenterology perspective

Journal of Digestive Diseases, 2020
An epidemic of an acute respiratory syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in Wuhan, China, now known as coronavirus disease 2019 (COVID‐19), beginning in December 2019, has attracted an intense amount of ...
Lianyong Li, Wei Wu, Sheng Chen, J. Gu, Xin Li, Haiyan Song, Feng Du, Gang Wang, Changqing Zhong, X. Wang, Yan Chen, R. Shah, H. Yang, Q. Cai   +13 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

The Relationship between Serum Zinc Level and Liver Elastrography Using Fibroscan in Non-Alcoholic Fatty Liver Patients

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2018
BACKGROUND AND OBJECTIVE: Zinc is one of the essential elements for many vital functions of the body, including regulation of gene expression, anti-inflammatory and antioxidant activity, protein and nucleic acids metabolism.
E Hajiani, A Parsi, K Erfanian Taghvaie, M Morvaridi   +3 more
doaj  

Impact of gastrointestinal symptoms and psychological distress on quality of life in systemic sclerosis: a cross-sectional study

BMJ Open
Background Systemic sclerosis (SSc) is a chronic autoimmune disease characterised by microvascular damage and fibrosis. Mortality in patients with SSc has significantly decreased.
Claudia Barber, Ariadna Aguilar, Alfredo Guillén-Del-Castillo, Luis Gerardo Alcala-Gonzalez, Claudia Codina, Antonio Marin Garcia, Carolina Malagelada, Carmen P Simeon-Aznar   +7 more
doaj   +1 more source

Infectious diseases as a factor of formation pathology of digestive organs in children

Детские инфекции (Москва), 2019
It has been shown that various infectious diseases can be a factor in the formation and development of pathology of the digestive system organs in children.The literature describes, mainly, the clinical aspect of changes in the organs of the digestive ...
L. S. Kalagina
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Epidemiology of Inflight Medical Events [PDF]

International Journal of Travel Medicine and Global Health, 2019
Introduction: Since the 1950s, air travel has grown exponentially. In 2018, the number of international air passengers was estimated at 4.1 billion. Air travel exposes the passenger to a number of constraints (like physical constraints, stress) that can ...
Gaetan Guiu, Jonathan Monin, Eric Perrier, Olivier Manen   +3 more
doaj   +1 more source