Results 41 to 50 of about 1,330,094 (399)

Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

Genetics, 2018
The gastrointestinal tract has recently come to the forefront of multiple research fields. It is now recognized as a major source of signals modulating food intake, insulin secretion and energy balance.
I. Miguel-Aliaga, H. Jasper, B. Lemaître   +2 more
semanticscholar   +1 more source

Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer

International Journal of Translational Medicine
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with poor survival even after surgical resection. Clinical stages include resectable (R-PDAC), borderline resectable (BR-PDAC), locally advanced, and metastatic disease ...
Julia Groszewska, Michał Romaniuk, Ewa Małecka-Wojciesko   +2 more
doaj   +1 more source

Procoagulant Disorders in Patients with Newly Diagnosed Pancreatic Adenocarcinoma

Medicina, 2020
Background and objectives: Cancer coagulopathy is thought to be partially due to the up-regulation of tissue factor (TF), thrombin-antithrombin complex (TAT) and soluble P-selectin (sP-selectin).
Renata Talar-Wojnarowska, Małgorzata Woźniak, Anna Borkowska, Katarzyna Cypryk, Marek Olakowski, Ewa Małecka-Panas   +5 more
doaj   +1 more source

PirABVP Toxin Binds to Epithelial Cells of the Digestive Tract and Produce Pathognomonic AHPND Lesions in Germ-Free Brine Shrimp

Toxins, 2019
Acute hepatopancreatic necrosis disease (AHPND), a newly emergent farmed penaeid shrimp bacterial disease originally known as early mortality syndrome (EMS), is causing havoc in the shrimp industry. The causative agent of AHPND was found to be a specific
Vikash Kumar, L. Bels, L. Couck, K. Baruah, P. Bossier, W. Broeck   +5 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Utilization of Channels Digestion Golden Snail (Pomacea Canaliculata) as Lytic Enzyme and Application on Yeast Pichia Manshurica DUCC-Y15 [PDF]

, 2015
Mollusks were one of invertebrate animals that have not been studied and used in in the field of enzyme. One type of mollusk that has not been exploited significantly is golden snail (Pomacea canaliculata), especially in the digestive ...
Hidayat, Jafron W., Parman, Sarjana, Wijanarka, W.   +2 more
core  

Plant cell walls: impact on nutrient bioaccessibility and digestibility [PDF]

, 2020
Cell walls are important structural components of plants, affecting both the bioaccessibility and subsequent digestibility of the nutrients that plant-based foods contain.
Edwards, Cathrina H., Grundy, Myriam M.-L., Holland, Claire, Ryden, Peter   +3 more
core   +3 more sources

Viral-Infected Change of the Digestive Tract Microbiota Associated With Mucosal Immunity in Teleost Fish

Frontiers in Immunology, 2019
The digestive tract is a unique series of organs that is inhabited by a range of commensal microbes while also exposed to an overwhelming load of dietary antigens.
Shuai Dong, L. Ding, Jia-feng Cao, Xia Liu, Hao-yue Xu, Kai-feng Meng, Yong-yao Yu, Qingchao Wang, Zhen Xu   +8 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Clinical Outcomes of Patients with Colorectal Cancer Who Underwent Comprehensive Genomic Profiling: A Single-institution Non-comparative Prospective Observational Study

Journal of the Anus, Rectum and Colon
Objectives: Although some studies have evaluated the effectiveness of comprehensive genomic profiling (CGP) in solid tumors, the effectiveness of CGP in metastatic colorectal cancer (mCRC) has not been evaluated using detailed real-world long-outcome ...
Yoshiko Mori, Okihide Suzuki, Noriko Tanabe, Aoi Sugino, Takehiro Shiraishi, Norimichi Chiyonobu, Kenichi Chikatani, Noriyasu Chika, Satoshi Hatano, Takatoshi Matsuyama, Keiichiro Ishibashi, Hideyuki Ishida   +11 more
doaj   +1 more source