Results 61 to 70 of about 83,154 (265)
Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes
eLife, 2015 An outstanding question is how receptor tyrosine kinases (RTKs) determine different cell-fate decisions despite sharing the same signalling cascades. Here, we uncovered an unexpected mechanism of RTK trafficking in this process.
Roberto Villaseñor +4 more
doaj +1 more source
Micro-Electro-Mechanical Systems in Light Stabilization
Sensors, 2023 This article discusses application considerations in the micro-electro-mechanical system’s optical sensor. Furthermore, the provided analysis is limited to application issues occurring in research or industrial applications.
Marian Gilewski
doaj +1 more source
Conversion from linear to circular polarization in FPGA
, 2010 Context: Radio astronomical receivers are now expanding their frequency range to cover large (octave) fractional bandwidths for sensitivity and spectral flexibility, which makes the design of good analogue circular polarizers challenging.
Das, Koyel +3 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
A capacitive mismatch calibration method for SAR ADCs based on TDC
Electronics LettersThe capacitance mismatch problem limits the accuracy improvement of high‐precision SAR ADCs (Successive Approximation Register Analog‐to‐Digital Converters).
Qing Shen +5 more
doaj +1 more source
Computer Aided Analysis of Turbine Blade Vibration Test Data
Measurement + Control, 1973 A pilot system has been developed which automatically scans and evaluates experimental vibration data obtained from a test rig replica of a bladed wheel of a turbine in service. High vibration amplitude signals are selected for further analysis.
F. L. N-Nagy, S. R. Taylor
doaj +1 more source
Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Digitizing UK analogue magnetogram records from large geomagnetic storms of the past two centuries
Geoscience Data Journal, 2023 Continuous geomagnetic records of the strength and direction of the Earth's field at the surface extend back to the 1840s. Over the past two centuries, eight observatories have existed in the United Kingdom, which measured the daily field variations ...
Ciaran D. Beggan +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source