Results 51 to 60 of about 2,282,773 (331)
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
BMGN - Low Countries Historical Review, 2013 Digital humanities seem to be omnipresent these days and the discipline of history is no exception. This introduction is concerned with the changing practice of ‘doing’ history in the digital age, seen within a broader historical context of developments in the digital humanities and ‘digital history’.
openaire +8 more sources
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
On digital simply connected spaces and manifolds: a digital simply connected 3-manifold is the digital 3-sphere [PDF]
arXiv, 2013 In the framework of digital topology, we study structural and topological properties of digital n-dimensional manifolds. We introduce the notion of simple connectedness of a digital space and prove that if M and N are homotopy equivalent digital spaces and M is simply connected, then so is N.
arxiv
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
arXiv, 2020 Digital Twins are one of the hottest digital trends. In this contribution we will shortly review the concept of Digital Twins and the chances for novel industrial applications. Mathematics are a key enabler and the impact will be highlighted along four specific examples addressing Digital Product Twins democratizing Design, Digital Production Twins ...
arxiv
Demonstration of a Standalone, Descriptive, and Predictive Digital Twin of a Floating Offshore Wind Turbine [PDF]
arXiv, 2023 Digital Twins bring several benefits for planning, operation, and maintenance of remote offshore assets. In this work, we explain the digital twin concept and the capability level scale in the context of wind energy. Furthermore, we demonstrate a standalone digital twin, a descriptive digital twin, and a prescriptive digital twin of an operational ...
arxiv
Nature Materials, 2014 Balancing the complexity and the simplicity has played an important role in the development of many fields in science and engineering. As Albert Einstein was once quoted to say: 'Everything must be made as simple as possible, but not one bit simpler'. The simplicity of an idea brings versatility of that idea into a broader domain, while its complexity ...
Nader Engheta +1 more
openaire +3 more sources