Results 41 to 50 of about 22,211 (263)

Digital Archaeology Archives in Portugal [PDF]

Internet Archaeology, 2021
Archaeology produces large quantities of data, much of it already in a born-digital format. The preservation of these data is vital, as they result from unrepeatable actions, and access to and sharing of these data are the engine of research activities and knowledge development.
openaire   +3 more sources

Self‐Assembled Calcite Architectures for Programmable Information Storage

Advanced Materials Technologies, EarlyView.
Programmable biomineralization enables the formation of 3D calcite architectures that encode information through spatially defined refractive‐index modulations. Data are written via laser‐directed mineralization, stored in stable voxelized mineral structures, and retrieved non‐destructively through optical diffraction, offering a pathway toward ultra ...
Congrui Jin, Yong Huang, Mehdi Ranjkesh Rashteh Roudi   +2 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Archiving in Advance of Mission Completion

Journal of Western Archives
This paper presents a detailed case study of the born-digital archiving efforts associated with the National Aeronautics and Space Administration's Origins, Spectral Interpretation, Resource Identification, and Security–Regolith Explorer (OSIRIS-REx ...
Molly Stothert-Maurer
doaj   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Digital video recording and archiving in ophthalmic surgery

Indian Journal of Ophthalmology, 2006
Currently most ophthalmic operating rooms are equipped with an analog video recording system [analog Charge Couple Device camera for video grabbing and a Video Cassette Recorder for recording)].
Raju Biju, Raju N, Raju Anju, Sudhakaran C, Razak Abdul   +4 more
doaj  

Assessing the effectiveness of digital archiving systems of higher education in Indonesia

Berkala Ilmu Perpustakaan dan Informasi
Introduction. This study explores factors influencing the effectiveness of digital archiving systems in Indonesian universities, aiming to improve search time, storage, and organization efficiency. Data Collection Method.
Herman Setyawan
doaj   +1 more source

Endings: Concluding, Archiving, and Preserving Digital Projects for Long-Term Usability

KULA, 2018
This report describes some of the practical solutions to the challenges of long-term digital preservation being developed by the project 'Endings: Concluding, Archiving, and Preserving Digital Projects for Long-Term Usability' at the University of ...
Claire Carlin
doaj   +1 more source