Results 41 to 50 of about 35,571,787 (246)

Hydrogel‐Based 3D‐Printed Anthropomorphic Breast Phantom for Emulating Mechanical and Dielectric Properties of Mammary Tissue. Applications in Microwave Imaging

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printable breast phantom is developed using patient‐derived MRI data and hydrogels that replicate the dielectric properties of healthy and cancerous tissues. Mechanical and dielectric characterization confirm its suitability for microwave imaging.
Carlos M. Andreu   +5 more
wiley   +1 more source

Status of digital standards, licensing types, and archiving policies in Asian open access journals registered in Directory of Open Access Journals [PDF]

open access: yesScience Editing, 2019
Purpose This study aims to analyze the digital standards of Asian journals registered in the Directory of Open Access Journals (DOAJ) which has been recognized as an index of quality for open access journals.
Soon Kim, Hyungwook Choi
doaj   +1 more source

Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation [PDF]

open access: yes, 2003
Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area.
Hedstrom, M.   +9 more
core  

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Archiving in Advance of Mission Completion

open access: yesJournal of Western Archives
This paper presents a detailed case study of the born-digital archiving efforts associated with the National Aeronautics and Space Administration's Origins, Spectral Interpretation, Resource Identification, and Security–Regolith Explorer (OSIRIS-REx ...
Molly Stothert-Maurer
doaj   +1 more source

Metadatapedia: A proposal for aggregating metadata on data archiving [PDF]

open access: yes, 2012
The open access movement has highlighted the barriers that exist for users to gain access to significant portions of the research literature. The open data approach seeks to extend the principles of open access to the data and code that supports the ...
Nichols, David M.   +6 more
core   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li   +11 more
wiley   +1 more source

Assessing the effectiveness of digital archiving systems of higher education in Indonesia

open access: yesBerkala Ilmu Perpustakaan dan Informasi
Introduction. This study explores factors influencing the effectiveness of digital archiving systems in Indonesian universities, aiming to improve search time, storage, and organization efficiency. Data Collection Method.
Herman Setyawan
doaj   +1 more source

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