Results 31 to 40 of about 323,338 (243)

Reclaiming Human Agency in the Age of Artificial Intelligence

open access: yesJournal of Moral Theology
The text, in continuity with the group’s previous publication and following _Antiqua et Nova_, highlights the difference between the prevailing AI definition of intelligence as rational action and problem-solving (often influenced by behaviorism and ...
AI Research Group of the Centre for Digital Culture   +2 more
doaj   +1 more source

Automation of Multi-Class Microscopy Image Classification Based on the Microorganisms Taxonomic Features Extraction

open access: yesJournal of Imaging
This study presents a unified low-parameter approach to multi-class classification of microorganisms (micrococci, diplococci, streptococci, and bacilli) based on automated machine learning.
Aleksei Samarin   +9 more
doaj   +1 more source

A Long-Tailed Image Classification Method Based on Enhanced Contrastive Visual Language

open access: yesSensors, 2023
To solve the problem that the common long-tailed classification method does not use the semantic features of the original label text of the image, and the difference between the classification accuracy of most classes and minority classes are large, the ...
Ying Song, Mengxing Li, Bo Wang
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Seasonal body image dissatisfaction: a bi-hemispheric panel analysis of social media users across 4 years

open access: yesEating and Weight Disorders
Purpose Seasonal body image refers to within-person variations in body image satisfaction that correspond with climatic seasonality (winter, spring, summer, and autumn). Previous cross-sectional research involving male participants from northern (UK, USA,
Justin Thomas   +5 more
doaj   +1 more source

Enduring Victoria: Iconoclasm and Restoration at the British Embassy in Tehran

open access: yes19, 2022
This article will address curatorial challenges faced by the Government Art Collection in the repatriation, conservation, and selection of a new display for the British ambassador’s residence in Tehran following an attack by Iranian protesters in 2011 ...
Andrew Parratt, Laura Maria Popoviciu
doaj   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Non-Contrast Brain CT Images Segmentation Enhancement: Lightweight Pre-Processing Model for Ultra-Early Ischemic Lesion Recognition and Segmentation

open access: yesJournal of Imaging
Timely identification and accurate delineation of ultra-early ischemic stroke lesions in non-contrast computed tomography (CT) scans of the human brain are of paramount importance for prompt medical intervention and improved patient outcomes.
Aleksei Samarin   +9 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Emotions in digital context: Finnish way of saying Pick me; we could make a good couple!

open access: yesRevista Teknokultura, 2012
The world has become thoroughly mediated. Dating ads are cultural representations for negotiations of shared cultural models and evident personal meanings given to hetero-relationship.
Anne Holappa
doaj   +1 more source

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