Results 41 to 50 of about 39,110,992 (291)

Seasonal body image dissatisfaction: a bi-hemispheric panel analysis of social media users across 4 years

open access: yesEating and Weight Disorders
Purpose Seasonal body image refers to within-person variations in body image satisfaction that correspond with climatic seasonality (winter, spring, summer, and autumn). Previous cross-sectional research involving male participants from northern (UK, USA,
Justin Thomas   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Digital cultural heritage [PDF]

open access: yes, 2013
What is the impact of media technology on the supply and demand of heritage with what is usually described as digitization? This chapter presents the concept of digitization as concerning far more than just the introduction of computers, the development of databases and websites, and the conversion of information to digital form.
openaire   +2 more sources

Non-Contrast Brain CT Images Segmentation Enhancement: Lightweight Pre-Processing Model for Ultra-Early Ischemic Lesion Recognition and Segmentation

open access: yesJournal of Imaging
Timely identification and accurate delineation of ultra-early ischemic stroke lesions in non-contrast computed tomography (CT) scans of the human brain are of paramount importance for prompt medical intervention and improved patient outcomes.
Aleksei Samarin   +9 more
doaj   +1 more source

HV-SNSP: A Low-Overhead Data Recovery Method Based on Cross-Checking

open access: yesIEEE Access, 2023
The failure of a single unreliable commodity component is very common in large-scale distributed storage systems. In order to ensure the reliability of data in large-scale distributed storage systems, many studies have emerged one after another.
Ying Song, Tiantong Mu, Bo Wang
doaj   +1 more source

Queer Digital Cultures

open access: yes, 2020
This chapter examines queer digital culture, a term that refers to the ways in which LGBTQ+ identities, practices, and theories have been mixed up in the emergence, design, and constitution of digital technology. It highlights significant shifts at the intersections of queer identity and politics and digital communication technologies from the 1980s to
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Long-Tailed Visual Recognition via Improved Cross-Window Self-Attention and TrivialAugment

open access: yesIEEE Access, 2023
In the real world, large-scale image data sets usually present long-tailed distribution. When traditional visual recognition methods are applied to long-tail image data sets, problems such as model failure and sudden decline in recognition accuracy occur.
Ying Song, Mengxing Li, Bo Wang
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Education in times of digital culture: opportunities and challenges

open access: yes, 2023
Education has been treated throughout its history as a space for experiences and innovations. In a time of digital culture, cyberspace and cyberculture are inescapable spaces, generating in educators and students the deterministic notion that there are ...
Gerson Leite de Moraes
core  

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