Results 41 to 50 of about 621,841 (302)

A Guide to Digital Medieval Studies in North America

open access: yesPerspectives Médiévales, 2016
This review article sets out to account for the role Digital Humanities plays in the editing of medieval texts in projects of Canadian and American digital medievalists.
Stephen P. McCormick
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Converged digital TV services: The role of middleware and future directions of interactive television [PDF]

open access: yes, 2009
The subject of the future of the interactive Television medium has become a topic of great interest to the academic and industrial communities particularly since in recent years there has been a dramatic increase in the pace of innovation of convergence ...
Tsekleves, Emmanuel   +26 more
core   +1 more source

Digital Editions and Version Numbering

open access: yesDigital Humanities Quarterly, 2020
Digital editions are easily modified after they are first published — a state of affairs that poses challenges both for long-term scholarly reference and for various forms of electronic distribution and analysis. This article argues that producers of digital editions should assign meaningful version numbers to their editions and update those version ...
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Soft Interventions

open access: yesTahiti, 2021
Recently there has been a growing number of artists working between photography and digital art, creating artworks in which the signs of digital operations have been left visible.
Jane Vuorinen
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A rationale of digital documentary editions [PDF]

open access: yesLiterary and Linguistic Computing, 2011
Publishing the diplomatic edition of a document on the web instead of in print implies a series of methodological and practical changes in the nature of the published text and in the operations to be performed by the editors. For print the choice of which features to include in the transcription is limited largely by the limits of the publishing ...
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Post-editing machine translated text in a commercial setting: Observation and statistical analysis [PDF]

open access: yes, 2010
Machine translation systems, when they are used in a commercial context for publishing purposes, are usually used in combination with human post-editing.
Tatsumi, Midori
core  

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