Results 81 to 90 of about 2,148,046 (305)
SystemsThe conceptual foundation of this research is the idea of convergence between such development directions of modern production systems as digital design tools and sustainable development.
Farida F. Galimulina +2 more
doaj +1 more source
Digital, material and networked: some emerging themes for SET education [PDF]
, 2015 Boundaries between the digital and material worlds are becoming blurred as the internet increasingly connects us to things as well as people and information.
Davies, Sarah-Jane +2 more
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
SystemsDigital transformation efforts as part of the Fourth Industrial Revolution promise to revolutionize engineering practices. However, given the multitude of technological choices and the diversity of potential investment decisions, many engineering ...
Joseph M. Campagna, Shamsnaz V. Bhada
doaj +1 more source
A metric to represent the evolution of CAD/analysis models in collaborative design [PDF]
, 2011 Computer Aided Design (CAD) and Computer Aided Engineering (CAE) models are often used during product design. Various interactions between the different models must be managed for the designed system to be robust and in accordance with initially defined ...
Dremont, Nicolas +4 more
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Generic PLM system for SMEs: Application to an equipment manufacturer [PDF]
, 2012 For several years, digital engineering has increasingly taken a more important place in the strategic issues of mechanical engineering companies.
BERNARD, Alain +3 more
core +8 more sources
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
SystemsThe Cyber Evaluation and Management Toolkit (CEMT) is an open-source university research-based plugin for commercial digital model-based systems engineering tools that streamlines conducting cybersecurity risk evaluations for complex cyber-physical ...
Stuart Fowler, Keith Joiner, Siqi Ma
doaj +1 more source