Results 81 to 90 of about 978,255 (310)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Re-engineering the management of human resources in university libraries [PDF]
, 2008 Information and Communication Technology application in university libraries poses several issues to be addressed, including those related to the management of human resources.
Humayoon Kabir, S., Francis, A. T.
core
A DIGITAL ENGINEERING CASE STUDY OF AN UNMANNED UNDERWATER VEHICLE [PDF]
, 2021 Team Icarus created a digital engineering case study based on an unmanned underwater vehicle (UUV) to provide a robust view of developing an architecture using Cameo Systems Modeler by executing the MagicGrid architecture development methodology.
Chheung, Tylong +5 more
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Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
SystemsThe Cyber Evaluation and Management Toolkit (CEMT) is an open-source university research-based plugin for commercial digital model-based systems engineering tools that streamlines conducting cybersecurity risk evaluations for complex cyber-physical ...
Stuart Fowler, Keith Joiner, Siqi Ma
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Digital service platform [PDF]
, 2020 The main objective of this project is to aid the Digital Transformation Efforts to realise the Smart Nation possibilities, of which this project is to streamline the process of creating and deploying digital services through this Digital Service ...
Shoh, Nigel De Wei
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Digital Tectonics as a Morphogenetic Process [PDF]
, 2010 p. 938-948Tectonics is a seminal concept that defines the nature of the relationship between architecture and its structural properties. The changing definition of the symbiotic relationship between structural engineering and architectural design may ...
OXMAN, Rivka
core +1 more source
Frontiers in Energy ResearchDigital engineering and digital twins are increasingly being used in nuclear energy projects with important impacts. At Idaho National Laboratory, these approaches have been applied in a variety of nuclear energy research, development, and demonstration ...
Ashley E. Finan +3 more
doaj +1 more source