Results 51 to 60 of about 41,339,345 (250)

Diving into Vernacular Digital Cultures

, 2023
This presentation aimed at reflecting on the history of vernacular digital cultures and their historical approach through web archives. It relied on the experience of the Hivi project (A history of Online Virality) and notably the historical study of ...
SCHAFER, Valerie
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Learning by Doing: Introducing Students to Public History through Digital Projects

, 2019
This article reflects on the process of building and teaching a course in digital public history for Bachelor students at the University of Luxembourg. The heart of the program was the hands-on, experimental approach.
Lucchesi, Anita , Legay, Richard   +1 more
core   +1 more source

Making sense of digital oral history

, 2019
Over the past three decades, oral history (OH) has been deeply transformed by the advent of digital technologies. The digital turn leads to growing number of online OH databases, resulting from “process-oriented” projects (i.e., life story interviews ...
BRONEC, Jakub
core   +1 more source

Digitales forum romanum: un progetto per la ricostruzione storico-scientifica in 3D del Foro Romano

Umanistica Digitale, 2019
Digitales forum romanum is a digital public history project promoted and developed by the Winckelmann Institute of the Humboldt University of Berlin, in collaboration with numerous institutions, not only German ones. Starting from the scientific research
Alessia Spadi
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Digital History studieren an der HU Berlin - Einladung zum Sommerschnuppern 2024

Das Sommerschnuppern geht in die dritte Runde. Wie schon in den vergangenen beiden Jahren möchte die Professur für Digital History am 13. Mai 2024, 18-20 Uhr, allen interessierten Bachelor- und Masterstudierenden in Berlin, aber auch darüber hinaus, im ...
Digital History Berlin (Redaktion)
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Introduction to Digital History

, 2021
Introduction to digital history for C²DH internal training program, focusing on the history of digital history and the ways in which digitised and digital heritage affects historical research (politics of digitisation)
ZAAGSMA, Gerben
core   +1 more source