Results 71 to 80 of about 1,709,733 (265)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Who's afraid of Patterns?: The Particular versus the Universal and the Meaning of Humanities 3.0

open access: yesBMGN: Low Countries Historical Review, 2013
The advent of Digital Humanities has enabled scholars to identify previously unknown patterns in the arts and letters; but the notion of pattern has also been subject to debate.
Rens Bod
doaj   +1 more source

For a New Hermeneutics of Practice in Digital Public History: Thinkering with memorecord.uni.lu

open access: yes, 2020
This thesis is built upon an experimental study of doing digital public history. I aim to study the digital interferences of the digital component on the historiographic operation as a whole. While the fields of digital and public history are advancing
LUCCHESI, Anita
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

A Coordinated Europeanization of the Comics Industry through Distribution: The Politics of the Global Journey of Astérix and Tintin through the Strategic Distribution of their Magazines and Contents in the 1960s

open access: yesOn_Culture, 2019
Researchers have usually focused on the Tintin and Astérix series’ global book diffusion through translation. However, little has been discussed about the distribution policies of the comics magazine format, a key factor in the development of European ...
Jessica Burton
doaj  

‘A Digital Archive of Ireland’s Ordnance Survey’: Connecting Collections for Nineteenth-Century Ireland

open access: yesJournal of Open Humanities Data
A three-year digital humanities research project, a collaboration between Queen’s University Belfast (QUB), the University of Limerick (UL) and the Digital Repository of Ireland (DRI), gathered historic Irish Ordnance Survey (OS) maps and texts into a ...
Lisa Griffith   +4 more
doaj   +1 more source

David B. Dennis & John Woitkowitz: Data Literacy and Digital Methods: Encoding Historical Sources with TEI/XML in the Classroom

open access: yes
This presentation discusses the “Exploring History and Digital Methods”-initiative and the experiences obtained from teaching data literacy and digital methods in the classroom. “Exploring History and Digital Methods” connects Dean College’s student body
Digital History Berlin (Redaktion)
core   +1 more source

Inside the Trading Zone: Thinkering in a Digital History Lab

open access: yes, 2020
peer reviewedThe goal of this article is to critically reflect on the practical and epistemological challenges of doing historical research in the digital age. The analysis is based on a case study of the Doctoral Training Unit (DTU) “Digital History and
FICKERS, Andreas, VAN DER HEIJDEN, Tim
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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