Results 31 to 40 of about 23,235 (228)
Digital Humanities or humanities in digital?
, 2020 The use of computing tools and methods has irreversibly impacted the creation, use and communication of research. As a result, a still divisive movement of Digital Humanities has emerged over the last few decades. This paper attempts to provide a theoretical contribution to the discussion of the core fundamentals of the field.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
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No Digital Citizens Without Digital Humanism
, 2023 AbstractUsing a Digital Humanism viewpoint when teaching informatics is the key to face the challenges posed to our society by digital technologies. This is particularly relevant for education in school, where children are going to learn about the basic principles and concepts of the discipline.
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Digital storytelling: New opportunities for humanities scholarship and pedagogy
Cogent Arts & Humanities, 2016 At first thought, combining storytelling, digital tools, and humanities seems improbable. For example, digital storytelling is characterized by interactivity, nonlinearity, flexible outcomes, user participation, even co-creation.
John F. Barber
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Umanistica Digitale, 2018 This paper introduces two projects in the realm of Digital Humanities, Mapping Visions of Rome and Digital Roman Heritage. The first project was conceived as a digital aid to my traditional research, while the second developed as a digital aid to the ...
Susanna de Beer
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
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Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
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Agilität, Versionierung und Open Source. Softwareentwicklung und Praktiken der Geisteswissenschaften
Zeitschrift für digitale Geisteswissenschaften, 2018 The Digital Humanities open up the possibility to access literary and historical sources in new ways. They enable the large-scale data analysis of cultural artifacts, which can be understood as the ...
Arndt Niebisch
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