Results 61 to 70 of about 30,122 (246)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
GraphEidos: A Dataset of Visual Rhetoric in Digital Humanities
This data article introduces GraphEidos, a new open-access dataset that documents how visuals have been used and discussed in digital humanities (DH) journal publications. The dataset covers various forms of visual representations, their captions, and in-
Rongqian Ma, Kai Li, Ranvir Singh Virk
doaj +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Who's afraid of Patterns?: The Particular versus the Universal and the Meaning of Humanities 3.0
The advent of Digital Humanities has enabled scholars to identify previously unknown patterns in the arts and letters; but the notion of pattern has also been subject to debate.
Rens Bod
doaj +1 more source
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Annotation of subtitle paraphrases using a new web tool
This paper analyzes the manual annotation effort carried out to produce Opusparcus, the Open Subtitles Paraphrase Corpus for six European languages. Within the scope of the project, a new web-based annotation tool was created.
Mikko Aulamo +2 more
doaj +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
One of the strong instruments for the promotion of Open Science in Digital Humanities is research infrastructures. PARTHENOS is a European research infrastructure project, basically built upon collaboration between two large the research ...
Bente Maegaard
doaj +1 more source

