Results 41 to 50 of about 399,318 (247)

The Urban Digital Platform: Instances from Milan and Amsterdam

Urban Planning, 2020
The article interrogates the concept of the urban in relation to digital platforms designed for citizen-based initiatives and local projects. We must broaden our scope as urban scholars to include this vast undergrowth of ‘other’ platforms and study how ...
Letizia Chiappini
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Mobile App Engagement and Effective Weight Management

Journal of Health Science and Medical Research (JHSMR)
Objective: This study aimed to investigate the relationship between mobile application engagement and lifestyle outcomes, specifically physical activity and dietary habits, during a 36-day virtual competition designed to promote healthier behaviors ...
Decho Surangsrirat, Warisara Asawaponwiput, Panyawut Sri-iesaranusorn, Nannapat Pruphetkaew, Polathep Vichitkunakorn   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Impact of central adiposity on the heart rate and calorie estimation accuracy of diverse smartwatches and the resulting subjective exercise experience

Frontiers in Sports and Active Living
IntroductionIn light of the growing global trend toward health awareness, wearable technologies like smartwatches have become essential for monitoring physiological indicators such as heart rate (HR). However, their utility faces two critical challenges:
Areenta Lertyongphati, Warunya Udomkhwamsuk, Nathakorn Amornrungrojanakul, Kanakorn Suk-ieam, Wimonrat Khamyan, Phinyo Chaengchit, Warisara Asawaponwiput, Polathep Vichitkunakorn, Polathep Vichitkunakorn, Decho Surangsrirat   +9 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A Digital Platform for Facilitating Personalized Dementia Care in Nursing Homes: Formative Evaluation Study

JMIR Formative Research, 2021
BackgroundCare personalization is key to the well-being of people with dementia according to person-centered care. With the development of the internet of things, a large quantity of personal data can be collected securely and reliably, which has the ...
Wang, Gubing, Albayrak, Armagan, Kortuem, Gerd, van der Cammen, Tischa JM   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Taxation of a digital monopoly platform [PDF]

Journal of Public Economic Theory, 2017
AbstractThis paper investigates the impact on fiscal revenues of taxing a two‐sided monopolistic platform offering personalized services to users and targeted advertising to sellers, based on the collection of users' personal data. We show that the introduction of a small tax on data collection, which has been proposed in the French context by Collin ...
Bourreau, Marc, Caillaud, Bernard, de Nijs, Romain   +2 more
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source