Results 41 to 50 of about 774,297 (295)

AI-Driven Digital Platform Innovation

open access: yesTechnology Innovation Management Review, 2020
Artificial Intelligence (AI) innovation becomes useful today when it enriches decision-making that is enhanced by applications of big data (BD), advanced analytics (AA), and some element of human interaction using digital platforms. This research aims to
Sergey A. Yablonsky
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Parkinson’s disease severity clustering based on gait activity from mobile device

open access: yesScientific Reports
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including gait impairments, which significantly affect patient mobility and quality of life.
Panyawut Sri-iesaranusorn   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Digital Industrial Platforms [PDF]

open access: yesBusiness & Information Systems Engineering, 2021
Tobias Pauli   +2 more
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Converged digital TV services: The role of middleware and future directions of interactive television [PDF]

open access: yes, 2009
The subject of the future of the interactive Television medium has become a topic of great interest to the academic and industrial communities particularly since in recent years there has been a dramatic increase in the pace of innovation of convergence ...
Tsekleves, Emmanuel   +26 more
core   +1 more source

A Digital Platform for Facilitating Personalized Dementia Care in Nursing Homes: Formative Evaluation Study

open access: yesJMIR Formative Research, 2021
BackgroundCare personalization is key to the well-being of people with dementia according to person-centered care. With the development of the internet of things, a large quantity of personal data can be collected securely and reliably, which has the ...
Wang, Gubing   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Exploring the needs of Malay manuscript studies community for an e-learning platform [PDF]

open access: yes, 2011
Philology studies are often associated with traditional methods of teaching and learning. This study explores the possibility of e-learning adoption amongst Malay manuscripts learning community.
Zainab, A.N.   +6 more
core  

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