Results 41 to 50 of about 3,753,769 (363)
Preserving Open Access Journals: A Literature Review [PDF]
This literature review addresses certain questions concerning the preservation of free, born-digital scholarly materials. It covers recent thinking on the current state of preservation efforts of born-digital materials; the range of actors involved in ...
Jottkandt, Sigi
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Digital Preservation and Access [PDF]
There is a crisis in the publication and archiving of archaeological field data in Europe. Computerized data are more fragile than paper archives but also more accessible via the Internet. This article explores the role of the Archaeology Data Service and examines some of the issues raised by the collection of digital data and their dissemination ...
openaire +1 more source
Digital Preservation Services : State of the Art Analysis [PDF]
Research report funded by the DC-NET project.An overview of the state of the art in service provision for digital preservation and curation. Its focus is on the areas where bridging the gaps is needed between e-Infrastructures and efficient and forward ...
Dobreva, Milena, Ruusalepp, Raivo
core
Toward Environmentally Sustainable Digital Preservation
Digital preservation relies on technological infrastructure (information and communication technology, ICT) that has considerable negative environmental impacts, which in turn threaten the...
Keith L. Pendergrass +3 more
semanticscholar +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Developing preservation processes for a trusted digital repository will require the integration of new methods, policies, standards, and technologies. Digital repositories should be able to preserve electronic materials for periods at least comparable to existing preservation methods. Modern computing technology in general is barely fifty years old and
Jantz, Ronald C., Giarlo, Michael
openaire +2 more sources
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
A Guide to Distributed Digital Preservation [PDF]
This volume is devoted to the broad topic of distributed digital preservation, a still-emerging field of practice for the cultural memory arena. Replication and distribution hold out the promise of indefinite preservation of materials without degradation,
Schultz, Matt, Skinner, Katherine
core +1 more source
Reuse remix recycle: repurposing archaeological digital data [PDF]
Preservation of digital data is predicated on the expectation of its reuse, yet that expectation has never been examined within archaeology. While we have extensive digital archives equipped to share data, evidence of reuse seems paradoxically limited ...
Huggett, Jeremy
core +1 more source

