Results 61 to 70 of about 1,684,857 (352)
Exploring the Consistent behavior of Information Services
MATEC Web of Conferences, 2016 Computer services are normally assumed to work well all the time. This usually happens for crucial services like bank electronic services, but not necessarily so for others, that there is no commercial interest in their operation.
Kapidakis Sarantos
doaj +1 more source
Back to basics: what is the e-journal? [PDF]
, 2004 As we move further into the first decade of a new century, it seems a good point to reflect on where the e-journal has come from, the position it is at now, and where it might be going in the immediate and long-term future. My concern within this article
Cole, Louise
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Developing virtual museums towards the smart museum: a theoretical study
Cybrarians JournalThe study focuses on the latest innovations in virtual applications and virtual reality devices for presenting museum information by reviewing the successive technological developments that have influenced virtual museums, leading to the smart museum ...
Marwa Abdelmajid
doaj +1 more source
Preventing rigour mortis: our migration to social media does not spell the end of academic rigour [PDF]
, 2012 Academic research involving social media is still perceived as less rigourous than traditional journal publishing. Alan Cann argues that while peer review remains the gold standard for quality research, we must apply this standard to the new unit of ...
Cann, Alan
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Osmanlı'dan Günümüze Türkiye'de Yerel Basının Gelişim Süreci
Selçuk İletişim, 2019 Osmanlı Devleti’nden bugüne Türk basınının yaygın ve yerel ölçekte değişen iletişim yöntemleri, ekonomik, siyasi ve toplumsal koşullara bağlı olarak çeşitli dönüşümler yaşamıştır.
Abdi Erkal, Olcay Uçak
doaj +1 more source
Glimmers of Digital Publishing Innovation
Refract: An Open Access Visual Studies Journal, 2023 As an exercise, take a moment to consider: What is the most innovative eBook or electronic publication that you have read in the past couple of years? Alternatively, what is the most innovative electronic publication, broadly speaking, that you have ever read? You might be asking, what does innovative have to do with it?
openaire +3 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source