Results 71 to 80 of about 1,540,423 (323)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Reference Librarian in Digital Environment:

Iranian Journal of Information Processing & Management, 2008
The information explosion of the latter half of the twentieth century, gave rise to online databases and various information media that gradually impacted on the very physical environment of the library. It transformed the librarians’ role.
Faramarz Sohili, Leila Khalili
doaj  

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

The Library Visit Study: user experiences at the virtual reference desk

Information Research: An International Electronic Journal, 2004
This paper discusses the methodology and reports on initial findings of a study examining the perceptions of users of digital reference services. It is part of a long-term research project, The Library Visit Study, which has been conducted in three ...
Nilsen Kirsti
doaj  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Μοντέλο λειτουργίας εικονικής βιβλιοθήκης για την ανάδειξη, παροχή και αξιοποίηση του τεχνολογικού κεφαλαίου του Ε.Μ.Π. [PDF]

, 2009
This paper seeks to establish a Virtual Library (VL) model. More specifically, a suggested model of a VL with technical digital content is described with regard to aggregating and displaying the research papers or data produced at National Technical ...
Κουής, Δημήτρης, Κόκκινος, Διονύσης   +1 more
core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

Frequency of use of the digital services in the library of the university polyclinic “Central Electronuclear”

Medisur, 2010
Background: Information and Communication Technologies (ICT) have pushed the evolution of library services and encouraged the development of libraries in the Primary Health Care System in Cuba, with the establishment of digital services.
María de los Reyes González Ramos, María Elinor Dulzaides Iglesias, Domingo Pérez Valladares, Martha Vázquez Villavicencio   +3 more
doaj   +2 more sources

Elementary, Middle, and High School Students Vary in Frequency and Purpose When Using Online Digital References. A review of: Silverstein, Joanne. “Just Curious: Children’s Use of Digital Reference for Unimposed Queries and Its Importance in Informal Education.” Library Trends 54.2 (Fall 2005): 228‐44.

Evidence Based Library and Information Practice, 2006
Objective – To determine 1) how and with what frequency children use digital references to answer their own unimposed questions; 2) whether digital reference services support their self‐initiated learning; 3) whether digital reference services support ...
Julie Stephens
doaj