Results 71 to 80 of about 1,233,556 (275)
Frontiers in Marine ScienceImplementing Part II of the Biodiversity Beyond National Jurisdiction (BBNJ) Agreement is an opportunity to transform the global approach to access and benefit sharing (ABS) of biological resources, digital sequence information and traditional knowledge.
Fran Humphries, Fran Humphries
doaj +1 more source
Brand Digital Development Strategy Based on Consumer Cognition and Behavior--Taking the clothing industry as an example [PDF]
SHS Web of ConferencesIn the era of rapid development of the digital economy, to enhance market competitiveness, digital transformation has been widely considered by major brands.
Yu Fanshu
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Kinematics in the Information Age
Mathematics, 2018 Modern kinematics derives directly from developments in the 1700s, and in their current instantiation, have been adopted as standard realizations…or templates that seem unquestionable.
Brendon Smeresky +2 more
doaj +1 more source
Realization of multiband communications using different Rydberg final states
AIP Advances, 2022 Rydberg atoms can serve as an atomic radio frequency receiver for digital and analog information transmission. In this paper, a ladder-type electromagnetically induced transparency system is prepared in a room temperature cesium atomic vapor cell ...
Yijie Du +6 more
doaj +1 more source
Data hidding in color images using perceptual models [PDF]
, 2000 One of the problems arising from the use of digital media is the ease of identical copies of digital images or audio files, allowing manipulation and unauthorized use.
Madueño Ruíz, María Isabel +2 more
core
Secure Communications using Nonlinear Silicon Photonic Keys
, 2018 We present a secure communication system constructed using pairs of nonlinear photonic physical unclonable functions (PUFs) that harness physical chaos in integrated silicon micro-cavities.
Bosworth, Bryan T. +5 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source