Results 81 to 90 of about 1,233,556 (275)

World Health Organization's Pathogen Access and Benefit‐Sharing system for digital sequence information and the Convention on Biological Diversity

Clinical and Translational Discovery
Background The World Health Organization Pandemic Agreement, adopted in May 2025, aims to remedy the inequities of the coronavirus disease 2019 pandemic.
WooJung Jon
doaj   +1 more source

Degraded Broadcast Diamond Channels with Non-Causal State Information at the Source

, 2012
A state-dependent degraded broadcast diamond channel is studied where the source-to-relays cut is modeled with two noiseless, finite-capacity digital links with a degraded broadcasting structure, while the relays-to-destination cut is a general multiple ...
Li, Min, Simeone, Osvaldo, Yener, Aylin
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Data Sovereignty and Open Sharing: Reconceiving Benefit-Sharing and Governance of Digital Sequence Information

Data Science Journal
There are ethical, legal, and governance challenges surrounding data, particularly in the context of digital sequence information (DSI) on genetic resources. I focus on the shift in the international framework, as exemplified by the CBD-COP15 decision on
Masanori Arita
doaj   +1 more source

Red Clump Stars in the Sagittarius Tidal Streams

, 2012
We have probed a section (l ~ 150, b ~ -60) of the trailing tidal arm of the Sagittarius dwarf spheroidal galaxy by identifying a sample of Red Clump stream stars.
Carrell, Kenneth, Chen, Yuqin, Wilhelm, Ronald   +2 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Digital sequence information–legal questions for patent, copyright, trade secret protection and sharing of genomic sequencing data

IOP Conference Series: Earth and Environmental Science, 2020
Abstract Advances in sciences–both in molecular biology and information technology–have enabled new understandings of genetic resources and biological processes which lead to an ongoing fundamental paradigm shift. The phenomenon of big data resulting from genomic sequencing has emerged as a consequence of next generation sequencing ...
openaire   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source