Results 31 to 40 of about 3,734,160 (288)

Deep learning-based identification of patients at increased risk of cancer using routine laboratory markers

Scientific Reports
Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to determine the ...
Vivek Singh, Shikha Chaganti, Matthias Siebert, Sowmya Rajesh, Andrei Puiu, Raj Gopalan, Jamie Gramz, Dorin Comaniciu, Ali Kamen   +8 more
doaj   +1 more source

Teaching with digital technology [PDF]

ZDM, 2020
AbstractIn this survey paper, we describe the state of the field of research on teaching mathematics with technology with an emphasis on the secondary school phase. We synthesize themes, questions, results and perspectives emphasized in the articles that appear in this issue alongside the relevant foundations of these ideas within the key journal ...
Clark-Wilson, Alison, Robutti, Ornella, Thomas, Mike   +2 more
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Prediction uncertainty estimates elucidate the limitation of current NSCLC subtype classification in representing mutational heterogeneity

Scientific Reports
The heterogeneous pathogenesis and treatment response of non-small cell lung cancer (NSCLC) has led clinical treatment decisions to be guided by NSCLC subtypes, with lung adenocarcinoma and lung squamous cell carcinoma being the most common subtypes ...
Andrei Puiu, Carlos Gómez Tapia, Maximilian E. R. Weiss, Vivek Singh, Ali Kamen, Matthias Siebert   +5 more
doaj   +1 more source

Chest-scale self-compensated epidermal electronics for standard 6-precordial-lead ECG

npj Flexible Electronics, 2022
Six chest leads are the standardized clinical devices of diagnosing cardiac diseases. Emerging epidermal electronics technology shift the dangling wires and bulky devices to imperceptible wearing, achieving both comfortable experience and high-fidelity ...
Lang Yin, Youhua Wang, Jian Zhan, Yunzhao Bai, Chao Hou, Junfeng Wu, Rong Huang, Yuzhou Wang, YongAn Huang   +8 more
doaj   +1 more source

Inland Navigation Technology \u2709 - Digital Technology Impact on Safety and Efficiency [PDF]

, 2009
This workshop discussed the impact of digital technology on inland navigation safety and efficiency from the combined perspective government agencies and waterway operators.
Alexander, Lee
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Enhancing Literacy Instruction through Technology [PDF]

, 2018
Technology has altered how children experience language. As technology has taken root in society, literacy skills have expanded beyond simply reading and writing print texts to include interacting with digital texts and media.
Haugen, Kaylin M
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

DIGITAL TECHNOLOGY IN PHOTOGRAMMETRY

Journal of Engineering, 2005
One of the major advantages of digital photogrammetry is the potential to automate production processes efficiently, thus substantially improving the price performance ratio for photogramnetric products.
Fanar Mansour
doaj   +1 more source