Results 51 to 60 of about 43,125,470 (302)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Co-ordinate-based positional embedding that captures resolution to enhance transformer’s performance in medical image analysis

Scientific Reports
Vision transformers (ViTs) have revolutionized computer vision by employing self-attention instead of convolutional neural networks and demonstrated success due to their ability to capture global dependencies and remove spatial biases of locality.
Badhan Kumar Das, Gengyan Zhao, Saahil Islam, Thomas J. Re, Dorin Comaniciu, Eli Gibson, Andreas Maier   +6 more
doaj   +1 more source

DIGITAL TECHNOLOGY IN PHOTOGRAMMETRY

Journal of Engineering, 2005
One of the major advantages of digital photogrammetry is the potential to automate production processes efficiently, thus substantially improving the price performance ratio for photogramnetric products.
Fanar Mansour
doaj   +1 more source

Idecomp: imbalance-aware decomposition for class-decomposed classification using conditional GANs

Discover Artificial Intelligence, 2023
Medical image classification tasks frequently encounter challenges associated with class imbalance, resulting in biased model training and suboptimal classification performance.
Patryk Buczek, Usama Zidan, Mohamed Medhat Gaber, Mohammed M. Abdelsamea   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Digital ureteroscopes: technology update

Research and Reports in Urology, 2017
Chad M Gridley, Bodo E Knudsen Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH, USA Abstract: The field of ureteroscopy has undergone a continual evolution since the first ureteroscopes were introduced.
Gridley CM, Knudsen BE
doaj  

Multi-plane vision transformer for hemorrhage classification using axial and sagittal MRI data

Scientific Reports
Identifying brain hemorrhages from magnetic resonance imaging (MRI) is a critical task for healthcare professionals. The diverse nature of MRI acquisitions with varying contrasts and orientation introduces complexity in identifying hemorrhage using ...
Badhan Kumar Das, Gengyan Zhao, Boris Mailhe, Thomas J. Re, Dorin Comaniciu, Eli Gibson, Andreas Maier   +6 more
doaj   +1 more source

Chest-scale self-compensated epidermal electronics for standard 6-precordial-lead ECG

npj Flexible Electronics, 2022
Six chest leads are the standardized clinical devices of diagnosing cardiac diseases. Emerging epidermal electronics technology shift the dangling wires and bulky devices to imperceptible wearing, achieving both comfortable experience and high-fidelity ...
Lang Yin, Youhua Wang, Jian Zhan, Yunzhao Bai, Chao Hou, Junfeng Wu, Rong Huang, Yuzhou Wang, YongAn Huang   +8 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

ArtifactOps and ArtifactDL: a methodology and a language for conceptualizing and operationalising different types of pipelines

Journal of Cloud Computing: Advances, Systems and Applications
Machine learning is already integrated in diverse domains enhancing their performance and decision support. For laboratories, this approach is normally sufficient.
Raúl Miñón, Josu Diaz-de-Arcaya, Ana I. Torre-Bastida, Juan López-de-Armentia, Gorka Zarate, Lander Bonilla, Asier Garcia-Perez, Jon Aguirre-Usandizaga   +7 more
doaj   +1 more source