Results 41 to 50 of about 43,125,470 (302)

Humanization of digital technologies

open access: yesHuman Technology
This editorial introduces the special issue arising from the "11th International Conference on Communities and Technologies - Humanisation of Digital Technologies". It sets the stage for a series of papers that illustrate a shift from technology-centred to human-centred approaches in the development of digital technologies. The editorial highlights the
Siemon Dominik, Wolff Annika
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

An Exploration of Digital Technology over a Number of Manipulated Textile Surfaces [PDF]

open access: yes
Ink jet printing for textiles has brought many benefits to the textile print industry. It has an ability to print on demand, using thousands of colours, and at reduced costs compared with rotary screenprinting for small scale production, ink jet ...
Ryall, Helen
core   +4 more sources

Telehealth and Digital Technology

open access: yesTelehealth and Medicine Today, 2018
No abstract available. Editor’s note: This is the first in a series of articles by Dr. Englander that will discuss different elements of the value chain—where we are today, where there are gaps, and what the most innovative companies are doing to ...
Libbe Englander
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Digital stethoscope: technology update

open access: yesMedical Devices: Evidence and Research, 2018
Supreeya Swarup,1 Amgad N Makaryus1,2 1Department of Cardiology, Nassau University Medical Center, East Meadow, NY, 2Department of Cardiology, Zucker School of Medicine at Hofstra/Northwell Health, Hempstead, NY, USA Abstract: Cardiovascular disease (CVD)
Swarup S, Makaryus AN
doaj  

How artificial intelligence can enable data classification for market sizing - Insights from applications in practice

open access: yesInternational Journal of Information Management Data Insights
Determining the size of the addressable market is a key aspect of market intelligence and requires identifying and delineating projected budget data from potential customers.
L. Stallings   +4 more
doaj   +1 more source

A Modular Heuristic-Based Solution for Large-Scale Outage Management in Nuclear Power Plants [PDF]

open access: yesEPJ Web of Conferences
The Resource Constrained Project Scheduling Problem (RCPSP) is a prominent combinatorial optimization problem in academia. It involves scheduling project activities while considering constraints arising from logical relationships between tasks, resource ...
Ninpan Khwansiri   +9 more
doaj   +1 more source

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