Results 111 to 120 of about 6,051,419 (361)

Study on the impact of digital transformation on the innovation potential based on evidence from Chinese listed companies

open access: yesScientific Reports
Digital transformation has emerged as a powerful force in reshaping the business landscape and enabling organizations to enhance their capabilities. One critical aspect of this change is how it impacts an enterprise’s innovation ability.
Xu Zhao   +4 more
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A VLSI Array Architecture for Realization of DFT, DHT, DCT and DST

open access: yes, 2001
A unified array architecture is described for computation of DFT, DHT, DCT and DST using a modified CORDIC (CoOrdinate Rotation DIgital Computer) arithmetic unit as the basic Processing Element (PE).
Banerjee, Swapna   +2 more
core   +1 more source

The Strategic Role of Digital Transformation: Leveraging Digital Leadership to Enhance Employee Performance and Organizational Commitment in the Digital Era

open access: yesSyst.
Given the rapid advancements in the digital transformation era, digital leadership has become essential for enhancing employee performance and organizational commitment. This study specifically examines the mediating role of digital transformation in the
Guanming Qiao, Yannan Li, Ahreum Hong
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Digital leadership, business model innovation and organizational change: role of leader in steering digital transformation

open access: yesBenchmarking : An International Journal
PurposeScholars and practitioners acknowledge that digital leadership can help organizations gain a competitive advantage. This article focuses on the characteristics, styles and skills needed for effective digital leadership.
Mehreen Malik   +3 more
semanticscholar   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

NASA's Digital Transformation (DT) Initiative [PDF]

open access: yes
NASA's Digital Transformation (DT) Initiative will dramatically enhance NASA's mission impact by reinventing mission and mission support processes, products, and capabilities, enabled by an innovation culture, digital-savvy workforce, and advanced ...
Barthelemy, J.-F., Biegel, Bryan
core   +1 more source

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