Results 91 to 100 of about 73,966 (319)

Metaverse Framework Designing for Energy Scheduling in Energy Internet of Things Considering Emergence [version 2; peer review: 1 approved, 3 approved with reservations, 1 not approved]

Digital Twin
The traditional scheduling approach, which primarily considers energy oligarchs like large-scale loads and large-scale generators, is challenged by the rapid rise of distributed energy resources (DERs) in energy internet of things (EIoT).
Yechen HAN, Wenjing ZHANG, Yuanjun ZUO, Zhuo CHEN, Qian Ai, Xing He, Haihong ZHANG   +6 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

MicroMap: a network visualisation resource for human microbiome metabolism

npj Biofilms and Microbiomes
The human microbiome critically influences metabolism and thereby our health. Constraint-based reconstruction and analysis (COBRA) is a proven framework for generating mechanism-derived hypotheses along the nutrition-host-microbiome-disease axis. However,
Cyrille C. Thinnes, Renee Waschkowitz, Eoghan Courtney, Eoghan Culligan, Katie Fahy, Ruby A. M. Ferrazza, Ciara Ferris, Angeline Lagali, Rebecca Lane, Colm Maye, Olivia Murphy, David Noone, Saoirse Ryan, Mihaela Bet, Maria C. Corr, Hannah Cummins, David Hackett, Ellen Healy, Nina Kulczycka, Niall Lang, Luke Madden, Lynne McHugh, Ivana Pyne, Ciara Varley, Niamh Harkin, Ronan Meade, Grace O’Donnell, Bram Nap, Filippo Martinelli, Almut Heinken, Ines Thiele   +30 more
doaj   +1 more source

Modeling and Simulating Cities with Digital Twins

, 2022
The digital twin concept has virtually exploded in recent years, but within the built environment the traditional term has long been ‘3D city model’. However, the digital twin concept is increasingly gaining acceptance as a useful concept that extends ...
Logg, Anders,, Naserentin, Vasilis,
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Modeling of cross-scale human activity for digital twin workshop [version 2; peer review: 2 approved]

Digital Twin
Digital Twin Workshop(DTW), as an important approach to digitalization and intelligentization of workshop, has gained significant attention in manufacturing industry.
Liang Fu, Pei Zhang, Mengming Xia, Ke Chen, Tingyu Liu, Yifeng Sun, Qing Hong   +6 more
doaj   +1 more source

Digital Twins for Cities: A State of the Art Review

, 2020
During the last decades, a variety of digital tools have been developed to support both the planning and management of cities, as well as the inclusion of civic society.
Ketzler, Bernd, Zangelidis, Christoforos, Thuvander, Liane, Thuvander, Liane,, Logg, Anders,, Zangelidis, Christoforos,, Logg, Anders, Latino, Fabio,, Ketzler, Bernd,, Naserentin, Vasilis,, Naserentin, Vasilis, Latino, Fabio   +11 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Author Correction: First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

Scientific Reports, 2023
Bruno Frackowiak, Vincent Van den Bosch, Zoi Tokoutsi, Marco Baragona, Martijn de Greef, Aaldert Elevelt, Peter Isfort   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source