Results 81 to 90 of about 3,378,227 (313)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Digital TwinBackground It is currently observed that some landfills are experiencing severe overloading, with some having ceased operations. However, they continue to threaten the environment and public health.
Zehua Zhang +3 more
doaj +1 more source
A review of the technology standards for enabling digital twin [version 1; peer review: 2 approved]
Digital Twin, 2022 In the process of developing digital twin enabling applications, a lack of reference to standards related to digital twin terms, architecture and models leads to differences between users' understanding of digital twin, and it is difficult to realize the
Kai Wang +5 more
doaj +1 more source
A Survey on Digital Twin: Definitions, Characteristics, Applications, and Design Implications
IEEE Access, 2019 When, in 1956, Artificial Intelligence (AI) was officially declared a research field, no one would have ever predicted the huge influence and impact its description, prediction, and prescription capabilities were going to have on our daily lives.
B. Barricelli, E. Casiraghi, D. Fogli
semanticscholar +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Una procedura per l’Historic Digital Twin (HDT) dei ponti ad arco in muratura/ A procedure for Heritage Digital Twin (HDT) of masonry arch bridges. [PDF]
, 2021 The research presented here aims to define an operational procedure for analysing historic masonry arch bridges and developing digital replicas. Through the integration of different disciplines and tools, the digital model of the historic bridge of Fossa
Savini F. +4 more
core
Nano-Micro LettersHighlights With the incessant down-scaling of electronics, traditional semiconductors like Si are encountered with insurmountable hurdles to maintain performance increase without bringing about additional issues of power consumption escalating, in this ...
Laixiang Qin, Li Wang
doaj +1 more source
Digital Twin, 2022 The interest in defining and implementing Digital Twins (DT) is at the forefront of today’s product organizations. The evolution of increasingly complex systems requires that their information be organized and managed via digital twins. In addition, the
Michael Grieves
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Current Trends in Digital Twin Development, Maintenance, and Operation: An Interview Study [PDF]
This talk is based on our paper entitled “Current Trends in Digital Twin development, maintenance, and operation: An interview study” published in the Journal of Software and Systems Modeling in April ...
Haverkort, Boudewijn +10 more
core +1 more source