Results 61 to 70 of about 3,509,576 (320)

From Digital Twins to Digital Twin Prototypes: Concepts, Formalization, and Applications [PDF]

open access: yesIEEE Access
The transformation to Industry 4.0 also transforms the processes of developing intelligent manufacturing production systems. Digital twins may be employed to advance the development of these new (embedded) software systems.
Alexander Barbie, Wilhelm Hasselbring
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A review of the technology standards for enabling digital twin [version 1; peer review: 2 approved]

open access: yesDigital Twin, 2022
In the process of developing digital twin enabling applications, a lack of reference to standards related to digital twin terms, architecture and models leads to differences between users' understanding of digital twin, and it is difficult to realize the
Kai Wang   +5 more
doaj   +1 more source

Flight test results for the Digital Integrated Automatic Landing Systems (DIALS): A modern control full-state feedback design [PDF]

open access: yes, 1984
The Digital Integrated Automatic Landing System (DIALS) is discussed. The DIALS is a modern control theory design performing all the maneuver modes associated with current autoland systems: localizer capture and track, glideslope capture and track ...
Hueschen, R. M.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer

open access: yesScientific Reports
Pancreatic cysts, particularly intraductal papillary mucinous neoplasms (IPMNs), pose a potential risk for progressing to pancreatic cancer (PC). This study investigates the genetic architecture of benign pancreatic cysts and its potential connection to ...
A. K. M. Firoj Mahmud   +7 more
doaj   +1 more source

Digital Twins along the product lifecycle: A systematic literature review of applications in manufacturing [version 2; peer review: 2 approved, 2 approved with reservations]

open access: yesDigital Twin
Background The evolution of product expectations in the era of mass personalization implies an improvement and a better control of individualized creation and production processes throughout the product lifecycle.
Frédérique Mayer   +3 more
doaj   +1 more source

Intelligent digital twins and the development and management of complex systems [version 1; peer review: 4 approved]

open access: yesDigital Twin, 2022
The interest in defining and implementing Digital Twins (DT) is at the forefront of today’s product organizations. The evolution of increasingly complex systems requires that their information be organized and managed via digital twins.  In addition, the
Michael Grieves
doaj   +1 more source

DIGITAL TWINS: Video demonstration (digital twin)

open access: yes, 2017
DIGITAL TWINS. Project funded by the Valencian Institute of Business Competitiveness (IVACE) and European Union through the European Regional Development Fund (ERDF), within the public grant program adressed to Technological Institutes of the Valencian Community for the development of non-economic R&D projects carried out in cooperation with ...
openaire   +1 more source

Digital twins for conservation - Digital twin strategy

open access: yes, 2023
The digital documentation process that was addressed for the knowledge, conservation and management of Pier Luigi Nervi’s Turin Exhibition Center reflected the complexity of the object and required an immense effort to develop a novel, holistic approach, tailored to the strong, interdisciplinary nature of the research.
Giacomo Patrucco   +3 more
openaire   +1 more source

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