Results 51 to 60 of about 73,966 (319)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
npj Systems Biology and ApplicationsKinetic parameters such as the turnover number (k cat) and Michaelis constant (K M) are essential for modelling enzymatic activity but experimental data remains limited in scale and diversity. Previous methods for predicting enzyme kinetics typically use
Saleh Alwer, Ronan M. T. Fleming
doaj +1 more source
Building Digital Twin Data Model Based on Public Data
BuildingsThis study aims to propose a method for constructing basic digital twin data in South Korea by adhering to international standards and by utilizing publicly available data.
Dawoon Jeong +3 more
doaj +1 more source
Digital Twin, 2023 Background: Online laboratories that provide online experimentation are crucial for education and research in all fields of engineering. As a transformative technology, the digital twin can be potentially applied into online laboratories to enable ...
Zhongcheng Lei +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Nano-Micro LettersHighlights With the incessant down-scaling of electronics, traditional semiconductors like Si are encountered with insurmountable hurdles to maintain performance increase without bringing about additional issues of power consumption escalating, in this ...
Laixiang Qin, Li Wang
doaj +1 more source
Digital TwinBackground It is currently observed that some landfills are experiencing severe overloading, with some having ceased operations. However, they continue to threaten the environment and public health.
Zehua Zhang +3 more
doaj +1 more source
A review of the technology standards for enabling digital twin [version 1; peer review: 2 approved]
Digital Twin, 2022 In the process of developing digital twin enabling applications, a lack of reference to standards related to digital twin terms, architecture and models leads to differences between users' understanding of digital twin, and it is difficult to realize the
Kai Wang +5 more
doaj +1 more source
ComputersThe rapid development of digitalization, the Internet of Things (IoT), and Industry 4.0 has led to the emergence of the digital twin concept. IoT is an important pillar of the digital twin. The digital twin serves as a crucial link, merging the physical and digital territories of Industry 4.0.
April Lia Hananto +6 more
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source