Results 121 to 130 of about 337,845 (323)

Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality

Journal of Translational Medicine
Background Characterization of shared cancer mechanisms have been proposed to improve therapy strategies and prognosis. Here, we aimed to identify shared cell–cell interactions (CCIs) within the tumor microenvironment across multiple solid cancers and ...
Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Martin Smelik, Oleg Sysoev, Yunzhang Wang, A. K. M. Firoj Mahmud, Dina Mansour Aly, Mikael Benson   +8 more
doaj   +1 more source

Digital twin and its applications in the construction industry: A state-of-art systematic review [version 3; peer review: 1 approved, 5 approved with reservations]

Digital Twin
The construction industry has a great impact on social and economic development because of its wide coverage and a large number of stakeholders involved. It is precisely owing to its large volume that technological innovation of the construction industry
Ray Y. Zhong, Shuaiming Su, Yishuo Jiang
doaj   +1 more source

New Voices: What Works [PDF]

, 2010
Reviews grantees' accomplishments in building community news sites, keys to sustainability, and lessons learned about engagement, staffing, business models, social media, technology, partnerships, and limitations of university, youth, and radio ...
Jan Schaffer
core  

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

A Digital Twin Framework for Nuclear Power Equipment Maintenance: Design, Prototyping, and Preliminary Validation [version 2; peer review: 3 approved, 3 approved with reservations]

Digital Twin
Throughout the lifecycle of Nuclear Power Equipment (NPE), maintaining high-safety maintenance services is essential for optimal operation. Traditional time-based maintenance strategies are limited in NPE contexts due to stringent safety requirements and
Qingfeng Xu, Qian Huang, Fengtian Chang, Yifan Zhi, Min Zhang, Guanghui Zhou, Chao Zhang   +6 more
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Generative discovery of partial differential equations by learning from math handbooks

Nature Communications
Data-driven discovery of partial differential equations (PDEs) is a promising approach for uncovering the underlying laws governing complex systems.
Hao Xu, Yuntian Chen, Rui Cao, Tianning Tang, Mengge Du, Jian Li, Adrian H. Callaghan, Dongxiao Zhang   +7 more
doaj   +1 more source

Application of digital twin for industrial process control: A case study of gauge-looper-tension optimized control in strip hot rolling [version 2; peer review: 2 approved]

Digital Twin
During the hot rolling process, the performance of most control systems gradually degrades due to equipment aging and changing process conditions. However, existing gauge-looper-tension control method remain restricted by a lack of intelligent parameter ...
Shang Chen, Jie Sun, Wen Peng, Cheng-yan Ding, Dian-hua Zhang   +4 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Roughness prediction of end milling surface for behavior mapping of digital twined machine tools [version 2; peer review: 2 approved, 1 approved with reservations]

Digital Twin
Background The quality of machined parts is considered as a relevant factor to evaluate the production performance of machine tools. For mapping the production performance into a digital twin machine tool, a virtual metrology model for surface roughness ...
Gedong Jiang, Suiyan Shang, Wenwen Tian, Zheng Sun, Jun Xu, Dawei Zhang, Chi Fai Cheung   +6 more
doaj   +1 more source