Results 101 to 110 of about 37,303,817 (298)

From digital twins to clinically trustworthy twins: a clinical-claim-based validation framework for personalized digital health

open access: yesFrontiers in Digital Health
Digital twins are increasingly presented as a computational foundation for personalized and preventive medicine, because they promise to integrate multimodal data into dynamic representations of patients, organs, diseases, or care pathways.
Alexandre Vallée
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Unveiling the potential of digital twins in homecare: A reflexive thematic analysis of older adults’ views

open access: yesDigital Health
Objectives A growing number of frail older adults live at home, placing increasing demands on health and social care systems. Digital twins may improve homecare services and support person-centred and integrated care. This study investigated older adults’
Sandra Saade   +4 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Towards integrated data control for digital twins in industry 4.0

open access: yes, 2020
The Digital Twin is currently a widely discussed topic for presenting and exchanging information on physical assets through vir- tual networks. Especially the digitisation of the manufacturing industry, Industry 4.0, drives the implementation of Digital ...
Bader, Sebastian R., Maleshkova, Maria
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Digital Twins in the Context of Ensuring Sustainable Industrial Development

open access: yesActa Informatica Pragensia
Background: Currently, there is a megatrend towards digitalisation and servitisation using digital technologies and digital twins to support the digital transformation of the economy. In the literature, new digital technologies are seen as creating added
Yuliia Biliavska, Valentyn Biliavskyi
doaj   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

Digital twins in traumatology and orthopedics: review of joint imaging and cost-effectiveness

open access: yesКлиническая практика
Digital twins are promising tool for personalized medicine in traumatology and orthopedics. Their use enables virtual modeling of joint pathology and treatment based on patient-specific biomechanical characteristics.
Aleksandr V. Pepelyaev   +7 more
doaj   +1 more source

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