Results 81 to 90 of about 37,303,817 (298)
Cognitive Mimetics and Human Digital Twins : Towards Holistic AI Design
, 2023 AI is replacing and supporting people in many intelligence-requiring tasks. Therefore, it is essential to consider the conceptual grounds of designing future technical artefacts and technologies for practical use.
Saariluoma, Pertti, Karvonen, Antero
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
A New Concept of Digital Twin Supporting Optimization and Resilience of Factories of the Future
Applied Sciences, 2020 In the context of Industry 4.0, a growing use is being made of simulation-based decision-support tools commonly named Digital Twins. Digital Twins are replicas of the physical manufacturing assets, providing means for the monitoring and control of ...
Adrien Bécue +4 more
doaj +1 more source
Digital twins for metrology; metrology for digital twins
Measurement Science and TechnologyAbstract Digital twinning is a rapidly growing area of research. Digital twins combine models and data to provide up-to-date information about the state of a system. They support reliable decision-making in fields such as structural monitoring and advanced manufacturing.
Louise Wright, Stuart Davidson
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Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Digital twins in logistics [PDF]
, 2023 The logistics industry has undergone significant transformation over the years, thanks to advancements in technology. One of the most promising technologies disrupting the industry is digital twins.
Voronov, G. A.
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Digital Twins in Software Engineering—A Systematic Literature Review and Vision
Applied SciencesDigital twins are a powerful consequence of digital transformation. In fact, they have been applied to many industries to enhance operations, predict needs, improve decision making, or optimize performance, even though the definition of digital twins is ...
Miguel A. Guinea-Cabrera +1 more
doaj +1 more source
CoRR, 2016 Multiple forms of digital transformation are imminent. Digital Twins represent one concept. It is gaining momentum because it may offer real-time transparency. Rapid diffusion of digital duplicates faces hurdles due to lack of semantic interoperability between architectures, standards and ontologies.
openaire +3 more sources
, 2023 To encourage discussion of the challenges hindering the design and implementation of digital twins, the authors have ranked them based on a systematic literature review combined with an expert survey.Urban Data ...
Janssen, Patrick (author) +3 more
core
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source