Results 91 to 100 of about 128,358 (272)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Leveraging digital twins for improved orthopaedic evaluation and treatment
Journal of Experimental OrthopaedicsPurpose The purpose of this article is to explore the potential of digital twin technologies in orthopaedics and to evaluate how their integration with artificial intelligence (AI) and deep learning (DL) can improve orthopaedic evaluation and treatment ...
Michael C. Dean +5 more
doaj +1 more source
The status quo and future prospects of digital twins for healthcare
EngMedicineDigital twin technology plays a pivotal role in driving the digital transformation of healthcare services. This review provides a comprehensive overview of the applications of digital twins in the healthcare sector.
Teng Li +4 more
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Toward a Fluid Dance in Seamless Dress: The Field of Pre- and Perinatal Development Challenges Researchers to Integrate Scientific and Spiritual Orientations [PDF]
, 2012 The response of humankind to mystery is explored here, relative to the historically sharp distinction between scientific and spiritual ways of knowing. The evolving image of a dancer in a half-male/half-female costume serves as a metaphor for the rapport
Axness, Marcy Wineman
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
International Journal of Adaptive and Innovative Systems, 2022 Yuhang Zhao +5 more
openaire +1 more source
, 2007 We experimentally investigate quadrature correlations between pump, signal, and idler fields in an above-threshold optical parametric oscillator. We observe new quantum correlations among the pump and signal or idler beams, as well as among the pump and ...
Cassemiro, K. N. +3 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Digital Twin’s Anatomy: A Cross-Sector Framework With Healthcare Validation
IEEE AccessDigital twins (DT) in manufacturing, healthcare, and across different industrial domains are often over-simplified as solely a virtual representation of a physical object or service.
Sina Namaki Araghi +4 more
doaj +1 more source