Results 51 to 60 of about 1,096,635 (280)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Corrosion Inhibitive Behaviour of Camellia Sinensis on Aluminium Alloy in H2SO4 [PDF]

, 2014
The effect of Camellia Sinensis (green tea) extract as a green inhibitor on the corrosion of aluminium alloy in 0.8M sulphuric acid was studied at room temperature.
Joseph, O. O, Loto, C. A., Loto, R. T., Popoola, A. P. I.   +3 more
core  

Predicting Clinically Significant Weight Loss in a Multimodal Commercial Digital Weight Management Program: Machine Learning Approach

Iproceedings, 2023
Background Generally, adherence to diet and physical activity in behavioral weight management programs predicts weight loss. Moreover, meeting attendance and platform or app use predict weight loss. Many weight-loss–prediction studies primarily use regression.
Richard Bannor, Sherry Pagoto, Michelle I Cardel, Alexandra Lee, Gary D Foster, Ran Xu   +5 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Weight Reduction Through a Digital Nutrition and Food Purchasing Platform Among Users With Obesity: Longitudinal Study

Journal of Medical Internet Research, 2020
BackgroundDigital nutrition apps that monitor or provide recommendations on diet have been found to be effective in behavior change and weight reduction among individuals with obesity.
Hu, Emily A, Nguyen, Viet, Langheier, Jason, Shurney, Dexter   +3 more
doaj   +1 more source

Adsorption and Inhibitive Properties of Camellia Sinensis for Aluminium Alloy in HCI [PDF]

, 2014
This study reports the effect of Camellia Sinensis (green tea) extract as a green inhibitor on the corrosion of aluminium alloy in 0.5M hydrochloric acid. Weight loss/corrosion rate and potential measurement techniques were used for the experimental work.
Joseph, O. O, Loto, C. A., Loto, R. T.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A systematic review of the behaviour change techniques and digital features in technology-driven type 2 diabetes prevention interventions

Digital Health, 2020
Objectives Our aim was to conduct a systematic review to determine which technology-driven diabetes prevention interventions were effective in producing clinically significant weight loss, and to identify the behaviour change techniques and digital ...
Luke Van Rhoon, Molly Byrne, Eimear Morrissey, Jane Murphy, Jenny McSharry   +4 more
doaj   +1 more source

Effect of zinc oxide on the corrosion inhibition of mild steel embedded in concrete in 3.5% NaCl solution [PDF]

, 2015
The effect of zinc oxide on the corrosion inhibition of mild steel embedded in concrete in 3.5% sodium chloride solution was investigated using potential measurement, pH and gravimetric methods.
Joseph, O. O, Loto, C. A., Loto, R. T., Popoola, A. P. I.   +3 more
core