Results 101 to 110 of about 4,133,519 (389)

Defining Digitalities I: What’s Digital about Digits?

open access: yes, 2023
Modern discourses emphasizes electronic immateriality as the defining feature of digital technology. The idea that digits might be digital when punched onto cards, or even written on a piece of pa- per, is no longer intuitive. Yet by reconstructing the context in which the categories of digital and analog were first distinguished histori- cally in the ...
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Trajectory Tracking Nonlinear Hybrid Control of Automated Guided Vehicles

open access: yesComplexity
Automated guided vehicles (AGVs), so necessary in industrial environments, require precise control of trajectory tracking to make accurate stops at logistics stations, such as loading stations, or to pick up or drop off trolleys, pallets, or racks.
Antonio Sánchez-Rodríguez   +3 more
doaj   +1 more source

How hand-made affects consumers’ perceived nutritional quality of organic food

open access: yesFrontiers in Nutrition
This study analyzed the impact of handmade in depth on consumers’ perceived nutritional quality of organic food through three experiments. Experiment 1 found that handmade significantly enhanced consumers’ positive perceptions of nutritional quality of ...
Qin Liu   +4 more
doaj   +1 more source

How do we teach Filmmaking – given the rapid changes in digital technology? [PDF]

open access: yes, 2012
“Gutenberg's concept of movable type transcended the medium used for the printing itself. Digital, perhaps, may prove to be paper to celluloid’s parchment.” [Murch, 1999] With the recent cessation of production of 35mm cinema cameras [Kaufman, 2011] and ...
Anderson, L
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Judicial review, reasons and technology: a glance at constitutionalism and democracy [PDF]

open access: yes, 2012
Judicial review reflects the level of commitment between constitutionalism and democracy in contemporary States. Yet democracy as the sovereign government of the people implies a tension with constitutionalism as the rule of law.
Karam de Chueiri, Vera
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A noncooperative game theory-based incentive model for scaling permissioned blockchain networks

open access: yesBlockchain: Research and Applications
Blockchain offers decentralization and data security in a trustless environment. Transaction details are logged to trace a transaction trail. Blockchain has multiple components that are crucial to overall performance.
Richard Lapin, Somnath Mazumdar
doaj   +1 more source

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